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Details on Person SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs

Class:IdReaction:5692775
_displayNameSEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs
_doReleaseTRUE
_timestamp2015-05-25 03:49:40
authored[InstanceEdit:5692748] Meloche, Sylvain, 2015-05-12
catalystActivity[CatalystActivity:5692774] protein serine/threonine kinase activity of SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:5692772] Rothfels, Karen, 2015-05-12
edited[InstanceEdit:5692861] Rothfels, Karen, 2015-05-13
input[DefinedSet:5692708] CDC42EP2,3,5 [cytosol] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:5692646] The extracellular signal-regulated kinase 3 (mitogen-activated protein kinase 6 [MAPK6])-MAPK-activated protein kinase 5 signaling complex regulates septin function and dendrite morphology
[LiteratureReference:5693482] Borg proteins control septin organization and are negatively regulated by Cdc42
[LiteratureReference:5693468] Here come the septins: novel polymers that coordinate intracellular functions and organization
modified[InstanceEdit:5693489] Rothfels, Karen, 2015-05-15
[InstanceEdit:5693867] Rothfels, Karen, 2015-05-18
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameSEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs
output[DefinedSet:5692695] p-CDC42EP2,3,5 [cytosol] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
releaseDate2015-06-17
releaseStatusNEW
reviewed[InstanceEdit:5692746] Mathien, Simon, 2015-05-12
[InstanceEdit:5692748] Meloche, Sylvain, 2015-05-12
[InstanceEdit:5692747] Soulez, Mathilde, 2015-05-12
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5695842] R-HSA-5692775.2
summation[Summation:5692773] MAPK6 and MAPKAPK5 directly phosphorylate the septin regulat...
(hasEvent)[Pathway:5687128] MAPK6/MAPK4 signaling [Homo sapiens]
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