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Details on Person AKR1A1 oxidises BaPtDHD to BaP-7,8-dione

Class:IdReaction:5692232
_displayNameAKR1A1 oxidises BaPtDHD to BaP-7,8-dione
_doReleaseTRUE
_timestamp2015-09-04 20:34:01
authored[InstanceEdit:5692240] Jassal, Bijay, 2015-05-11
catalystActivity[CatalystActivity:5692220] alcohol dehydrogenase (NADP+) activity of AKR1A1 [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:5692240] Jassal, Bijay, 2015-05-11
edited[InstanceEdit:5692240] Jassal, Bijay, 2015-05-11
input[SimpleEntity:5692212] BaPtDHD [cytosol]
[SimpleEntity:29366] NADP+ [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:5692219] The Role of Human Aldo-Keto Reductases in the Metabolic Activation and Detoxication of Polycyclic Aromatic Hydrocarbons: Interconversion of PAH Catechols and PAH o-Quinones
modified[InstanceEdit:6785238] Jassal, Bijay, 2015-06-26
[InstanceEdit:6785240] Jassal, Bijay, 2015-06-26
[InstanceEdit:6792911] Jassal, Bijay, 2015-08-28
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameAKR1A1 oxidises BaPtDHD to BaP-7,8-dione
output[SimpleEntity:29364] NADPH [cytosol]
[SimpleEntity:5692216] BaP-7,8-dione [cytosol]
releaseDate2015-09-22
releaseStatusNEW
reviewed[InstanceEdit:6785241] D'Eustachio, Peter, 2015-06-26
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:6796782] R-HSA-5692232.2
summation[Summation:5692241] Polycyclic aromatic hydrocarbons (PAHs) are pro-carcinogens ...
(hasEvent)[Pathway:156590] Glutathione conjugation [Homo sapiens]
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