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Details on Person XPC binds RAD23 and CETN2
Class:Id Reaction:5691004
_displayName XPC binds RAD23 and CETN2
_doRelease TRUE
_timestamp 2015-09-04 20:33:57
authored [InstanceEdit:110274] Gopinathrao, G, 2004-01-29 18:08:32 [InstanceEdit:110275] Hoeijmakers, JH, 2004-01-29 18:08:33 [InstanceEdit:5691003] Orlic-Milacic, Marija, 2015-05-04
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:5691003] Orlic-Milacic, Marija, 2015-05-04
edited [InstanceEdit:5691003] Orlic-Milacic, Marija, 2015-05-04
input [CandidateSet:5688130] RAD23 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:4570490] CETN2 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:67441] XPC [nucleoplasm] [Homo sapiens]
literatureReference [LiteratureReference:5688128] Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23 [LiteratureReference:5688134] A novel regulation mechanism of DNA repair by damage-induced and RAD23-dependent stabilization of xeroderma pigmentosum group C protein [LiteratureReference:5688127] Centrosome protein centrin 2/caltractin 1 is part of the xeroderma pigmentosum group C complex that initiates global genome nucleotide excision repair [LiteratureReference:5688129] Centrin 2 stimulates nucleotide excision repair by interacting with xeroderma pigmentosum group C protein
modified [InstanceEdit:5691014] Orlic-Milacic, Marija, 2015-05-04 [InstanceEdit:5696403] Orlic-Milacic, Marija, 2015-05-28 [InstanceEdit:6782740] Orlic-Milacic, Marija, 2015-06-08 [InstanceEdit:6783705] Orlic-Milacic, Marija, 2015-06-16 [InstanceEdit:6792501] Orlic-Milacic, Marija, 2015-08-24 [InstanceEdit:6792503] Orlic-Milacic, Marija, 2015-08-24 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name XPC binds RAD23 and CETN2
output [Complex:5691010] XPC:RAD23:CETN2 [nucleoplasm] [Homo sapiens]
releaseDate 2004-03-06
reviewed [InstanceEdit:6790576] Fousteri, Maria, 2015-08-03
reviewStatus [ReviewStatus:9821382] five stars
revised [InstanceEdit:5691003] Orlic-Milacic, Marija, 2015-05-04
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:6796778] R-HSA-5691004.2
summation [Summation:5690976] XPC is mutated in individuals with xeroderma pigmentosum fro...
(hasEvent) [Pathway:5696394] DNA Damage Recognition in GG-NER [Homo sapiens]
(inferredFrom) [Reaction:353524] XP-C binds to RAD23B forming a heterodimer [Gallus gallus]
(precedingEvent) [Reaction:5691006] XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site [Homo sapiens]
(replacementInstances) [_Deleted:6793524] Deletion of instance: 109948
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