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Details on Person Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER

Class:IdReaction:5691001
_displayNameRepair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER
_doReleaseTRUE
_timestamp2015-09-04 20:33:56
authored[InstanceEdit:110546] Gopinathrao, G, 2004-02-02 17:30:34
[InstanceEdit:110275] Hoeijmakers, JH, 2004-01-29 18:08:33
[InstanceEdit:6783704] Orlic-Milacic, Marija, 2015-06-16
catalystActivity[CatalystActivity:5690210] DNA-directed DNA polymerase activity of (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:5691002] Orlic-Milacic, Marija, 2015-05-04
edited[InstanceEdit:6783704] Orlic-Milacic, Marija, 2015-06-16
input[SimpleEntity:30555] dNTP [nucleoplasm]
[Complex:5690478] (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] [Homo sapiens]
literatureReference[LiteratureReference:5690036] Coordination of dual incision and repair synthesis in human nucleotide excision repair
[LiteratureReference:5690482] Replication protein A safeguards genome integrity by controlling NER incision events
[LiteratureReference:5690489] Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells
[LiteratureReference:6782218] Efficient PCNA complex formation is dependent upon both transcription coupled repair and genome overall repair
modified[InstanceEdit:5696403] Orlic-Milacic, Marija, 2015-05-28
[InstanceEdit:6782207] Orlic-Milacic, Marija, 2015-06-05
[InstanceEdit:6783705] Orlic-Milacic, Marija, 2015-06-16
[InstanceEdit:6783799] Orlic-Milacic, Marija, 2015-06-17
[InstanceEdit:6790537] Orlic-Milacic, Marija, 2015-08-11
[InstanceEdit:6792501] Orlic-Milacic, Marija, 2015-08-24
[InstanceEdit:6792503] Orlic-Milacic, Marija, 2015-08-24
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameRepair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER
output[SimpleEntity:113541] PPi [nucleoplasm]
[Complex:5690470] (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2004-03-06
reviewed[InstanceEdit:6790576] Fousteri, Maria, 2015-08-03
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:6783704] Orlic-Milacic, Marija, 2015-06-16
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:6796777] R-HSA-5691001.2
summation[Summation:5690982] In global genome nucleotide excision repair (GG-NER), as wel...
(hasEvent)[Pathway:5696397] Gap-filling DNA repair synthesis and ligation in GG-NER [Homo sapiens]
(inferredFrom)[Reaction:353526] Repair of ~27-30 bp long patch by DNA Pol Epsilon [Gallus gallus]
(precedingEvent)[Reaction:5690997] Ligation of newly synthesized repair patch to incised DNA in GG-NER [Homo sapiens]
(replacementInstances)[_Deleted:6793520] Deletion of instance: 109968
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