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Details on Person Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER

Class:Id	Reaction:5690991
_displayName	Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER
_doRelease	TRUE
_timestamp	2017-04-19 15:39:31
authored	[InstanceEdit:110546] Gopinathrao, G, 2004-02-02 17:30:34 [InstanceEdit:110275] Hoeijmakers, JH, 2004-01-29 18:08:33 [InstanceEdit:6783704] Orlic-Milacic, Marija, 2015-06-16
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5690992] Orlic-Milacic, Marija, 2015-05-04
edited	[InstanceEdit:6783704] Orlic-Milacic, Marija, 2015-06-16
goBiologicalProcess	[GO_BiologicalProcess:17146] nucleotide-excision repair, preincision complex stabilization
input	[Complex:109943] ERCC1:ERCC4 [nucleoplasm] [Homo sapiens] [Complex:5691043] GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:5689261] The comings and goings of nucleotide excision repair factors on damaged DNA [LiteratureReference:5689616] Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPA [LiteratureReference:5689611] The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways
modified	[InstanceEdit:5691049] Orlic-Milacic, Marija, 2015-05-04 [InstanceEdit:6782144] Orlic-Milacic, Marija, 2015-06-04 [InstanceEdit:6783705] Orlic-Milacic, Marija, 2015-06-16 [InstanceEdit:6783799] Orlic-Milacic, Marija, 2015-06-17 [InstanceEdit:6790528] Orlic-Milacic, Marija, 2015-08-11 [InstanceEdit:6790529] Orlic-Milacic, Marija, 2015-08-11 [InstanceEdit:6792501] Orlic-Milacic, Marija, 2015-08-24 [InstanceEdit:6792503] Orlic-Milacic, Marija, 2015-08-24 [InstanceEdit:8985728] Orlic-Milacic, Marija, 2017-04-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER
output	[Complex:5691046] GG-NER incision complex:Open bubble dsDNA [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:109955] Formation of ERCC1:XPF heterodimeric complex [Homo sapiens] [Reaction:5696465] USP45 deubiquitinates ERCC1 [Homo sapiens] [Reaction:5689317] Formation of the pre-incision complex in GG-NER [Homo sapiens] [Reaction:6790487] RNF111 ubiquitinates SUMOylated XPC [Homo sapiens]
releaseDate	2004-03-06
reviewed	[InstanceEdit:6790576] Fousteri, Maria, 2015-08-03
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:6783704] Orlic-Milacic, Marija, 2015-06-16
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6796773] R-HSA-5690991.3
summation	[Summation:5690975] ERCC1:ERCC4 (ERCC1:XPF) DNA endonuclease complex binds 5' to...
(hasEvent)	[Pathway:5696395] Formation of Incision Complex in GG-NER [Homo sapiens]
(precedingEvent)	[Reaction:5690990] 5'- incision of DNA by ERCC1:ERCC4 in GG-NER [Homo sapiens]
(replacementInstances)	[_Deleted:6793200] Deletion of instance: 109953
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