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Details on Person 5'- incision of DNA by ERCC1:ERCC4 in GG-NER

Class:Id	Reaction:5690990
_displayName	5'- incision of DNA by ERCC1:ERCC4 in GG-NER
_doRelease	TRUE
_timestamp	2024-05-15 21:36:44
authored	[InstanceEdit:73956] Joshi-Tope, G, 2003-07-14 15:01:00 [InstanceEdit:110275] Hoeijmakers, JH, 2004-01-29 18:08:33 [InstanceEdit:6783704] Orlic-Milacic, Marija, 2015-06-16
catalystActivity	[CatalystActivity:5691058] endonuclease activity of GG-NER incision complex:Open bubble dsDNA [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5690989] Orlic-Milacic, Marija, 2015-05-04
edited	[InstanceEdit:6783704] Orlic-Milacic, Marija, 2015-06-16
goBiologicalProcess	[GO_BiologicalProcess:17134] nucleotide-excision repair
input	[Complex:5691046] GG-NER incision complex:Open bubble dsDNA [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:5690036] Coordination of dual incision and repair synthesis in human nucleotide excision repair
modified	[InstanceEdit:5691065] Orlic-Milacic, Marija, 2015-05-04 [InstanceEdit:6783705] Orlic-Milacic, Marija, 2015-06-16 [InstanceEdit:6790529] Orlic-Milacic, Marija, 2015-08-11 [InstanceEdit:6792501] Orlic-Milacic, Marija, 2015-08-24 [InstanceEdit:6792503] Orlic-Milacic, Marija, 2015-08-24 [InstanceEdit:6793198] Orlic-Milacic, Marija, 2015-08-31 [InstanceEdit:9816782] Orlic-Milacic, Marija, 2022-09-13 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9910632] Orlic-Milacic, Marija, 2024-05-15
name	5'- incision of DNA by ERCC1:ERCC4 in GG-NER
output	[Complex:5691059] GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:5690991] Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER [Homo sapiens] [Reaction:109955] Formation of ERCC1:XPF heterodimeric complex [Homo sapiens] [Reaction:5689317] Formation of the pre-incision complex in GG-NER [Homo sapiens]
releaseDate	2004-03-06
reviewed	[InstanceEdit:6790576] Fousteri, Maria, 2015-08-03
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6796772] R-HSA-5690990.4
summation	[Summation:5690980] In global genome nucleotide excision repair (GG-NER), just l...
(hasEvent)	[Pathway:5696400] Dual Incision in GG-NER [Homo sapiens]
(precedingEvent)	[Reaction:5690213] DNA polymerases delta, epsilon or kappa bind the GG-NER site [Homo sapiens]
(replacementInstances)	[_Deleted:6793193] Deletion of instance: 73939
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