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Details on Person ACO1 binds 4Fe-4S

Class:IdReaction:5690873
_displayNameACO1 binds 4Fe-4S
_doReleaseTRUE
_timestamp2024-03-04 22:24:44
authored[InstanceEdit:5690883] Jassal, Bijay, 2015-04-30
catalystActivity[CatalystActivity:9861287] iron-sulfur cluster binding activity of ACO1 [cytosol]
catalystActivityReference[CatalystActivityReference:9861285] iron-sulfur cluster binding activity of ACO1 [cytosol] Crystal structure of human iron regulatory protein 1 as cytosolic aconitase
compartment[Compartment:70101] cytosol
created[InstanceEdit:5690883] Jassal, Bijay, 2015-04-30
edited[InstanceEdit:5690883] Jassal, Bijay, 2015-04-30
input[EntityWithAccessionedSequence:5690899] ACO1 [cytosol] [Homo sapiens]
[OtherEntity:5690881] 4Fe-4S [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:5690905] A regulated RNA binding protein also possesses aconitase activity
[LiteratureReference:5690889] Crystal structure of human iron regulatory protein 1 as cytosolic aconitase
[LiteratureReference:5690879] The bifunctional iron-responsive element binding protein/cytosolic aconitase: the role of active-site residues in ligand binding and regulation
modified[InstanceEdit:5691198] Jassal, Bijay, 2015-05-05
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:8952298] Jassal, Bijay, 2016-12-14
[InstanceEdit:8954301] Jassal, Bijay, 2017-01-06
[InstanceEdit:8954303] Jassal, Bijay, 2017-01-06
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9855363] Stephan, Ralf, 2023-12-02
[InstanceEdit:9861289] D'Eustachio, Peter, 2024-02-16
[InstanceEdit:9863712] D'Eustachio, Peter, 2024-03-04
nameACO1 binds 4Fe-4S
output[Complex:5690885] ACO1:4Fe-4S [cytosol] [Homo sapiens]
previousReviewStatus[ReviewStatus:9821384] two stars
regulatedBy[PositiveRegulation:9855362] Positive regulation by 'Fe2+ [cytosol]'
releaseDate2017-03-27
reviewed[InstanceEdit:8954302] D'Eustachio, Peter, 2017-01-06
[InstanceEdit:9861286] Hill, David P, 2024-02-16
[InstanceEdit:9863711] D'Eustachio, Peter, 2024-03-04
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8886792] R-HSA-5690873.3
structureModified[InstanceEdit:9855363] Stephan, Ralf, 2023-12-02
[InstanceEdit:9861289] D'Eustachio, Peter, 2024-02-16
summation[Summation:8952299] Iron and citrate are essential for the metabolism of most or...
(hasEvent)[Pathway:917937] Iron uptake and transport [Homo sapiens]
(precedingEvent)[Reaction:5690911] ACO1:4Fe-4S isomerises CIT to ISCIT [Homo sapiens]
(updatedInstance)[_UpdateTracker:9864244] Update Tracker - [Reaction:5690873] ACO1 binds 4Fe-4S - v88:[addCatalystActivity, addRegulator]
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No pathways have been reviewed or authored by ACO1 binds 4Fe-4S (5690873)
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