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Details on Person PPT1 hydrolyses palmitoylated proteins

Class:IdReaction:5690517
_displayNamePPT1 hydrolyses palmitoylated proteins
_doReleaseTRUE
_timestamp2024-04-12 19:41:45
authored[InstanceEdit:5690549] Jassal, Bijay, 2015-04-29
catalystActivity[CatalystActivity:5690547] palmitoyl-(protein) hydrolase activity of PPT1 [lysosomal lumen]
compartment[Compartment:161320] lysosomal lumen
created[InstanceEdit:5690549] Jassal, Bijay, 2015-04-29
crossReference[DatabaseIdentifier:9865939] RHEA:19234
edited[InstanceEdit:5690549] Jassal, Bijay, 2015-04-29
input[Complex:5690533] PALM:protein [lysosomal lumen]
[SimpleEntity:1605715] H2O [lysosomal lumen]
internalReviewed[InstanceEdit:9907566] D'Eustachio, Peter, 2024-04-12
isChimericFALSE
literatureReference[LiteratureReference:5690372] New players on the metabolic stage: How do you like Them Acots?
[LiteratureReference:5690404] The emerging role of acyl-CoA thioesterases and acyltransferases in regulating peroxisomal lipid metabolism
[LiteratureReference:5690397] Functional and structural properties of mammalian acyl-coenzyme A thioesterases
[LiteratureReference:5690527] Purification and properties of a palmitoyl-protein thioesterase that cleaves palmitate from H-Ras
[LiteratureReference:5690524] Molecular cloning and expression of palmitoyl-protein thioesterase
modified[InstanceEdit:5690553] Jassal, Bijay, 2015-04-29
[InstanceEdit:6785218] Jassal, Bijay, 2015-06-25
[InstanceEdit:6785240] Jassal, Bijay, 2015-06-26
[InstanceEdit:6792911] Jassal, Bijay, 2015-08-28
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9865937] D'Eustachio, Peter, 2024-03-20
[InstanceEdit:9907565] D'Eustachio, Peter, 2024-04-12
[InstanceEdit:9907580] D'Eustachio, Peter, 2024-04-12
namePPT1 hydrolyses palmitoylated proteins
H2O + S-hexadecanoyl-L-cysteinyl-(protein) => H(+) + hexadecanoate + L-cysteinyl-(protein)
output[SimpleEntity:5690516] PALM [lysosomal lumen]
[SimpleEntity:6785219] protein [lysosomal lumen]
[SimpleEntity:428040] H+ [lysosomal lumen]
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2015-09-22
releaseStatusNEW
reviewed[InstanceEdit:6785241] D'Eustachio, Peter, 2015-06-26
[InstanceEdit:9907581] Hill, David P, 2024-04-12
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:6796769] R-HSA-5690517.3
structureModified[InstanceEdit:9865937] D'Eustachio, Peter, 2024-03-20
summation[Summation:5690544] The maintenance/regulation of cellular levels of free fatty ...
(hasEvent)[Pathway:75105] Fatty acyl-CoA biosynthesis [Homo sapiens]
(updatedInstance)[_UpdateTracker:9910961] Update Tracker - [Reaction:5690517] PPT1 hydrolyses palmitoylated proteins - v89:[addOutput]
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No pathways have been reviewed or authored by PPT1 hydrolyses palmitoylated proteins (5690517)
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