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Details on Person USP3,SAGA deubiquitinate Histone H2A,H2B

Class:IdReaction:5690080
_displayNameUSP3,SAGA deubiquitinate Histone H2A,H2B
_doReleaseTRUE
_timestamp2018-12-18 19:52:31
authored[InstanceEdit:5688416] Jupe, Steve, 2015-04-16
catalystActivity[CatalystActivity:5690309] cysteine-type deubiquitinase activity of USP3,SAGA:Ub-histone H2A, Ub-histone H2B [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:5690100] Jupe, Steve, 2015-04-27
edited[InstanceEdit:8869523] Jupe, Steve, 2016-05-05
input[Complex:6782792] USP3,SAGA:Ub-histone H2A, Ub-histone H2B [nucleoplasm] [Homo sapiens]
[SimpleEntity:113518] H2O [nucleoplasm]
isChimericFALSE
literatureReference[LiteratureReference:5690178] Human USP3 is a chromatin modifier required for S phase progression and genome stability
modified[InstanceEdit:5690302] Jupe, Steve, 2015-04-28
[InstanceEdit:6781948] Jupe, Steve, 2015-06-03
[InstanceEdit:6782109] Jupe, Steve, 2015-06-04
[InstanceEdit:6782542] Jupe, Steve, 2015-06-08
[InstanceEdit:6782615] Jupe, Steve, 2015-06-08
[InstanceEdit:6782815] Jupe, Steve, 2015-06-09
[InstanceEdit:6782847] Jupe, Steve, 2015-06-09
[InstanceEdit:8869459] Jupe, Steve, 2016-05-04
[InstanceEdit:8869637] Jupe, Steve, 2016-05-06
[InstanceEdit:8871338] Jupe, Steve, 2016-05-16
[InstanceEdit:8871616] Weiser, JD
[InstanceEdit:9632449] Rothfels, Karen, 2018-12-18
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameUSP3,SAGA deubiquitinate Histone H2A,H2B
output[Complex:6782785] USP3,SAGA:Histone H2A,Histone H2B [nucleoplasm] [Homo sapiens]
[DefinedSet:68524] Ub [nucleoplasm] [Homo sapiens]
releaseDate2016-06-15
reviewed[InstanceEdit:8871339] Meldal, Birgit, 2016-05-16
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8873322] R-HSA-5690080.4
summation[Summation:5690101] USP3 dynamically associates with chromatin and deubiquitinat...
(hasEvent)[Pathway:5689880] Ub-specific processing proteases [Homo sapiens]
(updatedInstance)[_UpdateTracker:9777953] Update Tracker - [Reaction:5690080] USP3,SAGA deubiquitinate Histone H2A,H2B - v68:[add_removeOutput]
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