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Details on Person Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [nucleoplasm]

Class:Id	Complex:5687643
_displayName	Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [nucleoplasm]
_timestamp	2015-09-04 18:46:25
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5687645] Orlic-Milacic, Marija, 2015-04-08
hasComponent	[EntityWithAccessionedSequence:54745] FEN1 [nucleoplasm] [Homo sapiens] [Complex:5687515] POLQ homodimer [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:5687494] POLQ [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:5687494] POLQ [nucleoplasm] [Homo sapiens] [Complex:5649884] PARP1,PARP2 dimers [nucleoplasm] [Homo sapiens] [CandidateSet:5649876] PARP1,PARP2 [nucleoplasm] [Homo sapiens] [CandidateSet:5649876] PARP1,PARP2 [nucleoplasm] [Homo sapiens] [Complex:5687644] Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8 [nucleoplasm] [Homo sapiens] [Complex:5684097] RBBP8 homotetramer [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912399] RBBP8 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912399] RBBP8 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912399] RBBP8 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912399] RBBP8 [nucleoplasm] [Homo sapiens] [Complex:5687646] Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN [nucleoplasm] [Homo sapiens] [Complex:75164] MRN [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:59544] MRE11A [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:75160] RAD50 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:75163] NBN [nucleoplasm] [Homo sapiens] [OtherEntity:5687642] Extended microhomologous 3'-ssDNA overhans-flap-DSB [nucleoplasm]
isChimeric	FALSE
name	Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6795087] R-HSA-5687643.1
(input)	[Reaction:5687653] PARP1,PARP2 dimers bound to MMEJ sites autoPARylate [Homo sapiens]
(output)	[Reaction:5687640] POLQ extends annealed 3'-ssDNA overhangs in MMEJ [Homo sapiens]
(physicalEntity)	[CatalystActivity:5687652] NAD+ poly-ADP-ribosyltransferase activity of Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [nucleoplasm]
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No pathways have been reviewed or authored by Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [nucleoplasm] (5687643)