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Details on Person Defective SLC34A2 does not cotransport HPO4(2-), 3Na+ from extracellular region to cytosol
| Class:Id | FailedReaction:5687585 |
| _displayName | Defective SLC34A2 does not cotransport HPO4(2-), 3Na+ from extracellular region to cytosol |
| _doRelease | TRUE |
| _timestamp | 2020-06-26 14:03:30 |
| authored | [InstanceEdit:5687621] Jassal, Bijay, 2015-04-08 |
| catalystActivity | [CatalystActivity:9631800] sodium:phosphate symporter activity of SLC34A2 mutants [plasma membrane] |
| compartment | [Compartment:876] plasma membrane [Compartment:984] extracellular region |
| created | [InstanceEdit:5687621] Jassal, Bijay, 2015-04-08 |
| disease | [Disease:5651682] pulmonary alveolar microlithiasis |
| edited | [InstanceEdit:5687621] Jassal, Bijay, 2015-04-08 |
| entityFunctionalStatus | [EntityFunctionalStatus:5687598] loss_of_function of SLC34A2 mutants [plasma membrane] |
| input | [SimpleEntity:74113] Na+ [extracellular region] [SimpleEntity:74113] Na+ [extracellular region] [SimpleEntity:74113] Na+ [extracellular region] [SimpleEntity:109277] Pi [extracellular region] |
| literatureReference | [LiteratureReference:427624] Mutations in SLC34A2 cause pulmonary alveolar microlithiasis and are possibly associated with testicular microlithiasis [LiteratureReference:5687582] SLC34A2 Gene mutation of pulmonary alveolar microlithiasis: report of four cases and review of literatures [LiteratureReference:5687601] Pulmonary alveolar microlithiasis: a case report and review of the literature |
| modified | [InstanceEdit:5688016] Jassal, Bijay, 2015-04-13 [InstanceEdit:6791022] Jassal, Bijay, 2015-08-17 [InstanceEdit:9631717] Wu, G, 2018-12-12 [InstanceEdit:9692890] , 2020-07-03 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 |
| name | Defective SLC34A2 does not cotransport HPO4(2-), 3Na+ from extracellular region to cytosol |
| normalReaction |
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| releaseDate | 2015-09-22 |
| releaseStatus | NEW |
| reviewed | [InstanceEdit:6791021] D'Eustachio, Peter, 2015-08-17 |
| reviewStatus | [ReviewStatus:9821382] five stars |
| species | [Species:48887] Homo sapiens |
| stableIdentifier | [StableIdentifier:6797194] R-HSA-5687585.4 |
| summation | [Summation:5687618] The human gene SLC34A2 encodes NaPi-2b which is abundantly e... |
| (hasEvent) | [Pathway:5687583] Defective SLC34A2 causes PALM [Homo sapiens] |
| (updatedInstance) | [_UpdateTracker:9776803] Update Tracker - [FailedReaction:5687585] Defective SLC34A2 does not cotransport HPO4(2-), 3Na+ from extracellular region to cytosol - v74:[add_removeInput] [_UpdateTracker:9778067] Update Tracker - [FailedReaction:5687585] Defective SLC34A2 does not cotransport HPO4(2-), 3Na+ from extracellular region to cytosol - v68:[addCatalystActivity] |
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