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Details on Person TP53BP1 recruits DCLRE1C to ATM

Class:IdReaction:5686900
_displayNameTP53BP1 recruits DCLRE1C to ATM
_doReleaseTRUE
_timestamp2015-09-04 20:33:24
authored[InstanceEdit:5692524] Orlic-Milacic, Marija, 2015-05-12
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:5686903] Orlic-Milacic, Marija, 2015-04-05
edited[InstanceEdit:5692524] Orlic-Milacic, Marija, 2015-05-12
input[Complex:5686692] DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:RIF1:PAXIP1 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:5686712] DCLRE1C [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:5686707] A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci
[LiteratureReference:5686902] PTIP associates with Artemis to dictate DNA repair pathway choice
modified[InstanceEdit:5686923] Orlic-Milacic, Marija, 2015-04-05
[InstanceEdit:5692524] Orlic-Milacic, Marija, 2015-05-12
[InstanceEdit:5693279] Orlic-Milacic, Marija, 2015-05-14
[InstanceEdit:5693618] Orlic-Milacic, Marija, 2015-05-16
[InstanceEdit:6784817] Orlic-Milacic, Marija, 2015-06-22
[InstanceEdit:6792494] Orlic-Milacic, Marija, 2015-08-24
[InstanceEdit:6792497] Orlic-Milacic, Marija, 2015-08-24
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameTP53BP1 recruits DCLRE1C to ATM
output[Complex:5686907] DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:RIF1:PAX1IP:DCLRE1C [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2015-09-22
releaseStatusNEW
reviewed[InstanceEdit:5693179] Borowiec, James A, 2015-06-12
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:6796747] R-HSA-5686900.2
summation[Summation:5686905] TP53BP1 is required for the recruitment of DCLRE1C (ARTEMIS)...
(hasEvent)[Pathway:5693571] Nonhomologous End-Joining (NHEJ) [Homo sapiens]
(precedingEvent)[Reaction:5686704] Activated ATM phosphorylates DCLRE1C [Homo sapiens]
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