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Details on Person Activated ATM phosphorylates ABL1

Class:IdReaction:5686578
_displayNameActivated ATM phosphorylates ABL1
_doReleaseTRUE
_timestamp2015-09-04 20:33:17
authored[InstanceEdit:5692524] Orlic-Milacic, Marija, 2015-05-12
catalystActivity[CatalystActivity:5693530] protein serine/threonine kinase activity of p-S1981,Ac-K3016-ATM [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:5686581] Orlic-Milacic, Marija, 2015-04-02
edited[InstanceEdit:5692524] Orlic-Milacic, Marija, 2015-05-12
input[SimpleEntity:29358] ATP [nucleoplasm]
[EntityWithAccessionedSequence:5686579] ABL1 [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:217096] Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation
modified[InstanceEdit:5687761] Orlic-Milacic, Marija, 2015-04-08
[InstanceEdit:5692524] Orlic-Milacic, Marija, 2015-05-12
[InstanceEdit:5693209] Orlic-Milacic, Marija, 2015-05-14
[InstanceEdit:5693618] Orlic-Milacic, Marija, 2015-05-16
[InstanceEdit:6792494] Orlic-Milacic, Marija, 2015-08-24
[InstanceEdit:6792497] Orlic-Milacic, Marija, 2015-08-24
[InstanceEdit:6792791] Orlic-Milacic, Marija, 2015-08-27
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameActivated ATM phosphorylates ABL1
output[SimpleEntity:113582] ADP [nucleoplasm]
[EntityWithAccessionedSequence:5686576] p-S456-ABL1 [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2015-09-22
releaseStatusNEW
reviewed[InstanceEdit:5693179] Borowiec, James A, 2015-06-12
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:6796741] R-HSA-5686578.2
summation[Summation:5686577] ATM, activated in response to DNA damage in the form of doub...
(hasEvent)[Pathway:5693565] Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks [Homo sapiens]
(precedingEvent)[Reaction:5686587] ABL1 phosphorylates RAD52 [Homo sapiens]
[Reaction:8956659] ABL1 phosphorylates YAP1 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9775924] Update Tracker - [Reaction:5686578] Activated ATM phosphorylates ABL1 - v78:[modifyText]
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