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Details on Person Orlic-Milacic, Marija, 2015-04-01
| Class:Id | InstanceEdit:5686231 |
| _displayName | Orlic-Milacic, Marija, 2015-04-01 |
| _timestamp | 2015-04-01 05:05:26 |
| author | [Person:1169272] Orlic-Milacic, Marija |
| dateTime | 2015-04-01 09:05:25 |
| (modified) | [Summation:75216] Ligation of the crossed-strand intermediate results in the f... [OtherEntity:75220] Holliday structure [nucleoplasm] [Complex:5685826] D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] [Homo sapiens] [PathwayDiagram:5685945] Diagram of HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA), Defective homologous recombination repair (HRR) due to BRCA1 loss-of-function, Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function, Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function, Impaired BRCA2 binding to SEM1 (DSS1), Impaired BRCA2 binding to RAD51, Impaired BRCA2 binding to PALB2, and Impaired BRCA2 translocation to the nucleus [Complex:5686104] Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] [Homo sapiens] |
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No pathways have been reviewed or authored by Orlic-Milacic, Marija, 2015-04-01 (5686231)