Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm]

Class:IdComplex:5685162
_displayNameATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm]
_timestamp2015-09-04 18:45:15
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:5685154] Orlic-Milacic, Marija, 2015-03-25
hasComponent
isChimericFALSE
literatureReference[LiteratureReference:5685015] A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling
modified[InstanceEdit:5685180] Orlic-Milacic, Marija, 2015-03-25
[InstanceEdit:5685657] Orlic-Milacic, Marija, 2015-03-27
[InstanceEdit:5685991] Orlic-Milacic, Marija, 2015-03-31
[InstanceEdit:5687736] Orlic-Milacic, Marija, 2015-04-08
nameATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:6794999] R-HSA-5685162.1
(hasComponent)[Complex:5693547] p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] [Homo sapiens]
(input)[Reaction:5684882] CHEK1 is recruited to resected DNA DSBs [Homo sapiens]
[Reaction:5693561] RAD51 binds BRCA2 at resected DNA DSBs [Homo sapiens]
[Reaction:5693580] Association of RAD52 with the RPA complex at resected DNA DSBs [Homo sapiens]
[FailedReaction:9709571] BRCA2 mutants with BRC defects or a defect in the C-terminal RAD51 binding site do not bind RAD51 [Homo sapiens]
(output)[Reaction:5684887] Activation of CHEK1 at resected DNA DSBs [Homo sapiens]
[Reaction:5685156] ATR phosphorylates RPA2 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9901785] Update Tracker - [Complex:5685162] ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] - v75:[updateContainedComponent]
[_UpdateTracker:9904574] Update Tracker - [Complex:5685162] ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] - v84:[updateContainedComponent]
[Change default viewing format]
No pathways have been reviewed or authored by ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (5685162)
Follow Reactome