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Details on Person NAPSA, CTSH, PGA3-5 cleave pro-SFTPB

Class:Id	Reaction:5684864
_displayName	NAPSA, CTSH, PGA3-5 cleave pro-SFTPB
_doRelease	TRUE
_timestamp	2015-09-04 20:32:45
authored	[InstanceEdit:5684866] Jassal, Bijay, 2015-03-23
catalystActivity	[CatalystActivity:5685879] peptidase activity of NAPSA, CTSH, PGA3-5 [multivesicular body lumen]
compartment	[Compartment:3828046] multivesicular body lumen
created	[InstanceEdit:5684866] Jassal, Bijay, 2015-03-23
edited	[InstanceEdit:5684866] Jassal, Bijay, 2015-03-23
input	[EntityWithAccessionedSequence:5685255] pro-SFTPB [multivesicular body lumen] [Homo sapiens] [SimpleEntity:5685882] H2O [multivesicular body lumen] [SimpleEntity:5685882] H2O [multivesicular body lumen]
isChimeric	FALSE
literatureReference	[LiteratureReference:5685892] Napsin A, a member of the aspartic protease family, is abundantly expressed in normal lung and kidney tissue and is expressed in lung adenocarcinomas [LiteratureReference:5685900] Human surfactant polypeptide SP-B. Disulfide bridges, C-terminal end, and peptide analysis of the airway form [LiteratureReference:5685912] Nucleotide sequence of human preprocathepsin H, a lysosomal cysteine proteinase [LiteratureReference:5685896] A comparative study on the NH2-terminal amino acid sequences and some other properties of six isozymic forms of human pepsinogens and pepsins
modified	[InstanceEdit:5685202] Jassal, Bijay, 2015-03-26 [InstanceEdit:5685640] Jassal, Bijay, 2015-03-27 [InstanceEdit:5685873] Jassal, Bijay, 2015-03-30 [InstanceEdit:5685914] Jassal, Bijay, 2015-03-30 [InstanceEdit:5686308] Jassal, Bijay, 2015-04-01 [InstanceEdit:6791020] Jassal, Bijay, 2015-08-17 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	NAPSA, CTSH, PGA3-5 cleave pro-SFTPB
output	[EntityWithAccessionedSequence:5685910] SFTPB(201-279) [multivesicular body lumen] [Homo sapiens] [EntityWithAccessionedSequence:5685901] SFTPB(25-200) [multivesicular body lumen] [Homo sapiens] [EntityWithAccessionedSequence:5685911] SFTPB(280-381) [multivesicular body lumen] [Homo sapiens]
precedingEvent	[BlackBoxEvent:5684868] pro-SFTPC translocates from ER membrane to multivesicle body [Homo sapiens] [BlackBoxEvent:5683836] SFTPC gene produces pro-SFTPC protein [Homo sapiens]
releaseDate	2015-09-22
releaseStatus	NEW
reviewed	[InstanceEdit:6791021] D'Eustachio, Peter, 2015-08-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6796713] R-HSA-5684864.2
summation	[Summation:5685905] In the multivesicular body, surfactant precursor protein pro...
(hasEvent)	[Pathway:5683826] Surfactant metabolism [Homo sapiens]
(precedingEvent)	[Reaction:6791016] SFTPB binds itself [Homo sapiens]
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No pathways have been reviewed or authored by NAPSA, CTSH, PGA3-5 cleave pro-SFTPB (5684864)