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Details on Person p-MRN [nucleoplasm]

Class:Id	Complex:5682166
_displayName	p-MRN [nucleoplasm]
_timestamp	2015-05-25 03:14:36
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5682165] Orlic-Milacic, Marija, 2015-03-05
hasComponent	[EntityWithAccessionedSequence:59544] MRE11A [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:75160] RAD50 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:75237] p-S343-NBN [nucleoplasm] [Homo sapiens]
name	p-MRN MRE11:RAD50:p-S343-NBN MRE11:RAD50:p-S343-NBS1
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5695104] R-HSA-5682166.1
(hasComponent)	[Complex:5682175] DNA DSBs:p-MRN [nucleoplasm] [Homo sapiens] [Complex:5684116] 3' overhanging ssDNA-DSBs:p-MRN [nucleoplasm] [Homo sapiens] [Complex:5685658] D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] [Homo sapiens] [Complex:5685986] 3' short overhanging ssDNA-DSBs:p-MRN [nucleoplasm] [Homo sapiens] [Complex:5686226] Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] [Homo sapiens] [Complex:5686227] Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] [Homo sapiens] [Complex:5686428] Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] [Homo sapiens] [Complex:5686487] Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] [Homo sapiens] [Complex:5686620] DNA DSB with annealed 3' ssDNA overhangs and displaced flaps:p-MRN [nucleoplasm] [Homo sapiens] [Complex:9980018] p-RPA:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex [nucleoplasm] [Homo sapiens]
(output)	[Reaction:5686410] BLM mediates dissolution of double Holliday junction [Homo sapiens] [BlackBoxEvent:5686469] Resolution of D-loops cleaved by MUS81:EME1 or MUS81:EME2 [Homo sapiens] [BlackBoxEvent:5686483] Resolution of Holliday junctions cleaved by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) [Homo sapiens] [BlackBoxEvent:5686663] Completion of SSA [Homo sapiens] [Reaction:5693589] D-loop dissociation and strand annealing [Homo sapiens] [Reaction:5693599] Association of Ku heterodimer with ends of DNA double-strand break [Homo sapiens]
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No pathways have been reviewed or authored by p-MRN [nucleoplasm] (5682166)