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Details on Person ULK complex translocates to the ER

Class:IdReaction:5679239
_displayNameULK complex translocates to the ER
_doReleaseTRUE
_timestamp2020-04-02 10:42:07
authored[InstanceEdit:5671581] Jupe, Steve, 2015-02-02
compartment[Compartment:70101] cytosol
[Compartment:12045] endoplasmic reticulum membrane
created[InstanceEdit:5679261] Jupe, Steve, 2015-03-03
edited[InstanceEdit:5692984] Jupe, Steve, 2015-05-13
input[Complex:5675837] p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:5679257] Autophagosome formation--the role of ULK1 and Beclin1-PI3KC3 complexes in setting the stage
[LiteratureReference:5679211] Temporal analysis of recruitment of mammalian ATG proteins to the autophagosome formation site
modified[InstanceEdit:5682408] Jupe, Steve, 2015-03-06
[InstanceEdit:5683339] Jupe, Steve, 2015-03-13
[InstanceEdit:5683719] Jupe, Steve, 2015-03-16
[InstanceEdit:5692976] Jupe, Steve, 2015-05-13
[InstanceEdit:5693009] Jupe, Steve, 2015-05-13
[InstanceEdit:6793655] Jupe, Steve, 2015-09-03
[InstanceEdit:9612935] Varusai, Thawfeek, 2018-07-05
[InstanceEdit:9638325] Varusai, Thawfeek, 2019-03-05
[InstanceEdit:9681506] Varusai, Thawfeek, 2020-04-02
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameULK complex translocates to the ER
output[Complex:5682402] p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] [Homo sapiens]
precedingEvent
releaseDate2015-06-17
reviewed[InstanceEdit:5693008] Tooze, Sharon A, 2015-05-13
[InstanceEdit:6793656] Klionsky, Daniel J, 2015-09-03
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:9638297] Varusai, Thawfeek, 2019-03-05
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5695777] R-HSA-5679239.6
summation[Summation:5679290] The ULK complex is recruited to the membrane site of phagoph...
(hasEvent)[Pathway:1632852] Macroautophagy [Homo sapiens]
(precedingEvent)[Reaction:1632857] ULK1 phosphorylates AMBRA1:BECN1 complex [Homo sapiens]
[Reaction:5679205] ULK1 phosphorylates Beclin-1 [Homo sapiens]
[Reaction:5682431] Don't release - ULK1 phosphorylates ATG9 [Homo sapiens]
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