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Details on Person sBAFF,sAPRIL binds TACI,BCMA

Class:Id	Reaction:5676607
_displayName	sBAFF,sAPRIL binds TACI,BCMA
_doRelease	TRUE
_timestamp	2015-05-25 03:48:59
authored	[InstanceEdit:5668484] Garapati, Phani Vijay, 2015-01-26
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:5676601] Garapati, Phani Vijay, 2015-02-20
edited	[InstanceEdit:5668484] Garapati, Phani Vijay, 2015-01-26
input	[DefinedSet:5676954] sBAFF,sAPRIL trimers [extracellular region] [Homo sapiens] [DefinedSet:5676951] TAC1,BCMA [plasma membrane] [Homo sapiens] [DefinedSet:5676951] TAC1,BCMA [plasma membrane] [Homo sapiens] [DefinedSet:5676951] TAC1,BCMA [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5676527] Biologically active APRIL is secreted following intracellular processing in the Golgi apparatus by furin convertase [LiteratureReference:5676490] BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator [LiteratureReference:5676491] BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth
modified	[InstanceEdit:5676956] Garapati, Phani Vijay, 2015-02-20 [InstanceEdit:5692511] Garapati, Phani Vijay, 2015-05-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	sBAFF,sAPRIL binds TACI,BCMA sTNFSF13B,sTNFSF13 binds TNFRSF13B,TNFRSF17
output	[Complex:5676562] sBAFF,sAPRIL:3xTAC1,BCMA [plasma membrane] [Homo sapiens]
releaseDate	2015-06-17
releaseStatus	NEW
reviewed	[InstanceEdit:5692509] Ware, Carl F, Virgen-Slane, Richard, Rajput, Akhil, 2015-05-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5695768] R-HSA-5676607.2
summation	[Summation:5676471] B cell activating factor (BAFF also known as TNFSF13B) and a...
(hasEvent)	[Pathway:5669034] TNFs bind their physiological receptors [Homo sapiens]
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No pathways have been reviewed or authored by sBAFF,sAPRIL binds TACI,BCMA (5676607)