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Details on Person TRAF2:cIAP1/2 complex binds FN14:TWEAK

Class:Id	Reaction:5676598
_displayName	TRAF2:cIAP1/2 complex binds FN14:TWEAK
_doRelease	TRUE
_timestamp	2015-05-25 03:48:58
authored	[InstanceEdit:5668484] Garapati, Phani Vijay, 2015-01-26
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:5676588] Garapati, Phani Vijay, 2015-02-20
edited	[InstanceEdit:5668484] Garapati, Phani Vijay, 2015-01-26
input	[Complex:5675977] 3xFN14:sTWEAK,TWEAK homotrimer [plasma membrane] [Homo sapiens] [Complex:5668435] cIAP1,2:TRAF2:TRAF3:NIK [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5676414] The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation
modified	[InstanceEdit:5676601] Garapati, Phani Vijay, 2015-02-20 [InstanceEdit:5692511] Garapati, Phani Vijay, 2015-05-12 [InstanceEdit:5692519] Garapati, Phani Vijay, 2015-05-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TRAF2:cIAP1/2 complex binds FN14:TWEAK
output	[Complex:5676555] 3xFn14:TWEAK:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:5669023] TWEAK binds FN14 [Homo sapiens]
releaseDate	2015-06-17
releaseStatus	NEW
reviewed	[InstanceEdit:5692509] Ware, Carl F, Virgen-Slane, Richard, Rajput, Akhil, 2015-05-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5695766] R-HSA-5676598.2
summation	[Summation:5676429] The FN14 (TNFRSF12A) intracellular domain lacks the characte...
(hasEvent)	[Pathway:5676594] TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway [Homo sapiens]
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No pathways have been reviewed or authored by TRAF2:cIAP1/2 complex binds FN14:TWEAK (5676598)