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Details on Person 2xRANK binds RANKL,sRANKL trimer:RANK

Class:Id	Reaction:5676592
_displayName	2xRANK binds RANKL,sRANKL trimer:RANK
_doRelease	TRUE
_timestamp	2015-05-25 03:48:55
authored	[InstanceEdit:5668484] Garapati, Phani Vijay, 2015-01-26
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:5676588] Garapati, Phani Vijay, 2015-02-20
edited	[InstanceEdit:5668484] Garapati, Phani Vijay, 2015-01-26
entityOnOtherCell	[DefinedSet:5676542] RANKL,sRANKL trimer [plasma membrane] [Homo sapiens]
input	[Complex:5676553] RANK:RANKL,sRANKL trimer [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:5668756] TNFRSF11A [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:5668756] TNFRSF11A [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5676518] A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function [LiteratureReference:5676294] Structural and functional insights of RANKL-RANK interaction and signaling
modified	[InstanceEdit:5676601] Garapati, Phani Vijay, 2015-02-20 [InstanceEdit:5692511] Garapati, Phani Vijay, 2015-05-12 [InstanceEdit:5692519] Garapati, Phani Vijay, 2015-05-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	2xRANK binds RANKL,sRANKL trimer:RANK
output	[Complex:5676546] 3xRANK:RANKL,sRANKL trimer [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:5676589] RANKL,sRANKL trimer binds RANK [Homo sapiens]
releaseDate	2015-06-17
releaseStatus	NEW
reviewed	[InstanceEdit:5692509] Ware, Carl F, Virgen-Slane, Richard, Rajput, Akhil, 2015-05-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5695761] R-HSA-5676592.2
summation	[Summation:5676400] The binding of RANKL trimer to RANK causes the trimerization...
(hasEvent)	[Pathway:5676594] TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway [Homo sapiens]
(precedingEvent)	[Reaction:5676595] TRAFs bind RANK:RANKL [Homo sapiens]
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No pathways have been reviewed or authored by 2xRANK binds RANKL,sRANKL trimer:RANK (5676592)