Query author contributions in Reactome

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Details on Person Winkles, Jeffrey A

Class:Id	Person:5675988
_displayName	Winkles, Jeffrey A
_timestamp	2015-02-18 11:35:47
created	[InstanceEdit:5675985] Garapati, Phani Vijay, 2015-02-18
firstname	Jeffrey A
initial	JA
surname	Winkles
(author)	[LiteratureReference:5675965] TWEAK, a member of the TNF superfamily, is a multifunctional cytokine that binds the TweakR/Fn14 receptor [LiteratureReference:5675983] Full-length, membrane-anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF-kappaB pathway [LiteratureReference:5676414] The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation [LiteratureReference:9644368] Cdc42 and the guanine nucleotide exchange factors Ect2 and trio mediate Fn14-induced migration and invasion of glioblastoma cells [LiteratureReference:9662798] The tumor necrosis factor-like weak inducer of apoptosis (TWEAK)-fibroblast growth factor-inducible 14 (Fn14) signaling system regulates glioma cell survival via NFkappaB pathway activation and BCL-XL/BCL-W expression
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No pathways have been reviewed or authored by Winkles, Jeffrey A (5675988)