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Details on Person The MT1G gene is inducible by zinc, copper, and cadmium (Sad...
| Class:Id | Summation:5675910 |
|---|---|
| _displayName | The MT1G gene is inducible by zinc, copper, and cadmium (Sad... |
| _timestamp | 2015-09-19 09:59:54 |
| created | [InstanceEdit:5675905] May, Bruce, 2015-02-18 |
| modified | [InstanceEdit:6798601] May, Bruce, 2015-09-19 |
| text | The MT1G gene is inducible by zinc, copper, and cadmium (Sadhu and Gedamu 1988, Jahroudi et al. 1990, Bagheri et al. 2009) and metal response elements of the MT1G promoter are responsible for its induction by metals (Foster and Gedamu 1991, Joshi et al. 2005). In response to zinc the MREs of MT1G bind a nuclear factor (Foster and Gedamu 1991, Samson et al. 1995) later shown to be the MTF1:zinc complex (Joshi et al. 2005), which transactivates transcription. The MT1G promoter also contains a binding site for E2F which is responsible for induction of MT1G by VEGF (Foster and Gedamu 1991). |
| (summation) | [Reaction:5660529] MTF1 dimer:12Zn2+ binds MT1G gene [Homo sapiens] |
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No pathways have been reviewed or authored by The MT1G gene is inducible by zinc, copper, and cadmium (Sad... (5675910)
