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Details on Person MTF1 dimer:12Zn2+ binds MT1A gene

Class:Id	Reaction:5674960
_displayName	MTF1 dimer:12Zn2+ binds MT1A gene
_timestamp	2016-07-15 23:49:05
authored	[InstanceEdit:5674963] May, Bruce, 2015-02-09
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5674957] May, Bruce, 2015-02-14
edited	[InstanceEdit:5674963] May, Bruce, 2015-02-09
inferredFrom	[Reaction:5660529] MTF1 dimer:12Zn2+ binds MT1G gene [Homo sapiens] [Reaction:5660505] Mtf1 dimer:12Zn2+, Sp1, Ep300, and Nfi dimer bind Mt1 gene [Mus musculus] [Reaction:5660505] Mtf1 dimer:12Zn2+, Sp1, Ep300, and Nfi dimer bind Mt1 gene [Mus musculus]
input	[EntityWithAccessionedSequence:5660409] MT1A gene [nucleoplasm] [Homo sapiens] [Complex:5660456] MTF1 dimer:12Zn2+ [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5674712] Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes [LiteratureReference:5660316] Cytotoxicity of nitric oxide is alleviated by zinc-mediated expression of antioxidant genes [LiteratureReference:5660154] Comparative analysis of MTF-1 binding sites between human and mouse [LiteratureReference:6798600] Differential quantitative zinc-induced expression of human metallothionein isogenes in haematopoietic precursor cell lines
modified	[InstanceEdit:5684767] May, Bruce, 2015-03-23 [InstanceEdit:6798601] May, Bruce, 2015-09-19 [InstanceEdit:8879177] Wu, G, 2016-07-15
name	MTF1 dimer:12Zn2+ binds MT1A gene
output	[Complex:5660819] MTF1 dimer:12Zn2+:MT1A gene [nucleoplasm] [Homo sapiens]
precedingEvent	[BlackBoxEvent:5660525] MTF1 dimer:12Zn2+ translocates from cytosol to nucleus [Homo sapiens] [Reaction:5660494] MTF1 dimer binds zinc [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8885197] R-HSA-5674960.1
summation	[Summation:5674958] Based on the inducibility of the MT1A gene by zinc (Vandeghi...
(hasEvent)	[Pathway:5660489] MTF1 activates gene expression [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:5660516] Expression of MT1A [Homo sapiens]
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No pathways have been reviewed or authored by MTF1 dimer:12Zn2+ binds MT1A gene (5674960)