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Details on Person IL17RD binds p-2S MAP2Ks and MAPKs

Class:Id	Reaction:5674366
_displayName	IL17RD binds p-2S MAP2Ks and MAPKs
_doRelease	TRUE
_timestamp	2017-01-27 21:44:45
authored	[InstanceEdit:5674147] Rothfels, Karen, 2015-02-10
compartment	[Compartment:20699] Golgi membrane
created	[InstanceEdit:5674363] Rothfels, Karen, 2015-02-11
edited	[InstanceEdit:5674528] Rothfels, Karen, 2015-02-12
input	[EntityWithAccessionedSequence:5674277] IL17RD [Golgi membrane] [Homo sapiens] [DefinedSet:5672721] p-2S MAP2K homo/heterodimers [cytosol] [Homo sapiens] [DefinedSet:169291] MAPKs [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5674365] Identification of Sef, a novel modulator of FGF signalling [LiteratureReference:5674368] Sef is a feedback-induced antagonist of Ras/MAPK-mediated FGF signalling [LiteratureReference:1268087] Sef is a spatial regulator for Ras/MAP kinase signaling [LiteratureReference:5674364] Sef: a MEK/ERK catcher on the Golgi [LiteratureReference:5672246] Raf family kinases: old dogs have learned new tricks
modified	[InstanceEdit:5675232] Rothfels, Karen, 2015-02-15 [InstanceEdit:5678363] Rothfels, Karen, 2015-02-23 [InstanceEdit:5690607] Rothfels, Karen, 2015-04-29 [InstanceEdit:5691229] Rothfels, Karen, 2015-05-05 [InstanceEdit:5692883] Rothfels, Karen, 2015-05-13 [InstanceEdit:8959616] Orlic-Milacic, Marija, 2017-01-27 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	IL17RD binds p-2S MAP2Ks and MAPKs
output	[Complex:5674360] IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] [Homo sapiens]
precedingEvent	[Reaction:5672980] Dissociation of RAS:RAF complex [Homo sapiens] [Reaction:5672973] MAP2Ks phosphorylate MAPKs [Homo sapiens]
releaseDate	2015-06-17
releaseStatus	NEW
reviewed	[InstanceEdit:5690572] Roskoski, Robert Jr, 2015-04-28
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5695741] R-HSA-5674366.3
summation	[Summation:5674367] IL17RD, also known as SEF (similar expression to FGF), was i...
(hasEvent)	[Pathway:5674135] MAP2K and MAPK activation [Homo sapiens]
(precedingEvent)	[Reaction:5674373] MAP2Ks phosphorylate MAPK at the Golgi membrane [Homo sapiens]
(replacementInstances)	[_Deleted:6799074] Deletion of instance: 1268203 [_Deleted:6799076] Deletion of instance: 1268214
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No pathways have been reviewed or authored by IL17RD binds p-2S MAP2Ks and MAPKs (5674366)