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Details on Person p-2S MAP2K homo/heterodimers [cytosol]

Class:Id	DefinedSet:5672721
_displayName	p-2S MAP2K homo/heterodimers [cytosol]
_timestamp	2015-05-25 03:03:24
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5672722] Rothfels, Karen, 2015-02-05
hasMember	[Complex:5672705] p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] [Homo sapiens] [Complex:5672703] p-S218,S222 MAP2K1 dimer [cytosol] [Homo sapiens] [Complex:5672701] p-S222,S226 MAP2K2 dimer [cytosol] [Homo sapiens]
name	p-2S MAP2K homo/heterodimers
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5694901] R-HSA-5672721.1
(activeUnit)	[CatalystActivity:5672974] protein serine/threonine kinase activity of activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] [CatalystActivity:5674372] protein serine/threonine/tyrosine kinase activity of IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] [CatalystActivity:9656191] protein serine/threonine kinase activity of activated RAF1 mutant:scaffold:p-2S MAP2K:MAPK complex [plasma membrane]
(hasCandidate)	[CandidateSet:5672734] RAF activating kinases [plasma membrane] [Homo sapiens]
(hasComponent)	[Complex:5672723] activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] [Homo sapiens] [Complex:5672724] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] [Homo sapiens] [Complex:5674131] WDR83:LAMTOR2:LAMTOR3:activated RAF:p-2S MAP2K:p-T,Y MAPK complex [endosome membrane] [Homo sapiens] [Complex:5674360] IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] [Homo sapiens] [Complex:5674362] IL17RD:p-2S MAP2Ks:p-T,Y MAPKs [Golgi membrane] [Homo sapiens] [Complex:6802625] RAS:GTP: inactive p-RAF:p-2S MAP2Ks:MAPKs:scaffold proteins [plasma membrane] [Homo sapiens] [Complex:6802637] RAS:GTP:inactive p-RAF:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [plasma membrane] [Homo sapiens] [Complex:6802647] RAS:GTP:moderate kinase activity p-RAF:p-2S MAP2Ks:MAPKs:scaffold proteins [plasma membrane] [Homo sapiens] [Complex:6802648] RAS:GTP:moderate kinase activity p-RAF:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [plasma membrane] [Homo sapiens] [Complex:6802664] high kinase activity BRAF mutants:scaffold:p-2S MAP2K:MAPK complex [cytosol] [Homo sapiens] List all 22 refering instances
(input)	[Reaction:5674366] IL17RD binds p-2S MAP2Ks and MAPKs [Homo sapiens]
(output)	[Reaction:5672980] Dissociation of RAS:RAF complex [Homo sapiens] [Reaction:6802932] Dissociation of BRAF/RAF fusion complex [Homo sapiens] [Reaction:6803227] Dissociation of high activity BRAF complexes [Homo sapiens] [Reaction:6803230] Dissociation of moderate activity BRAF complexes [Homo sapiens] [Reaction:6803233] Dissociation of oncogenic RAS:RAF complex [Homo sapiens] [Reaction:6803234] Dissociation of paradoxically activated RAS:BRAF complexes [Homo sapiens] [BlackBoxEvent:9610154] Dissociation of phosphorylated MAP2Ks and MAPKs [Homo sapiens] [Reaction:9656209] Dissociation of RAS:RAF1 mutant complex [Homo sapiens]
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No pathways have been reviewed or authored by p-2S MAP2K homo/heterodimers [cytosol] (5672721)