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Details on Person IQGAP1 binds CLIP1 and microtubules

Class:Id	Reaction:5672329
_displayName	IQGAP1 binds CLIP1 and microtubules
_doRelease	TRUE
_timestamp	2017-03-18 02:10:00
authored	[InstanceEdit:5628889] Orlic-Milacic, Marija, 2014-10-24 [InstanceEdit:5668821] Rivero Crespo, Francisco, 2014-12-26
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:5672328] Orlic-Milacic, Marija, 2015-02-04
edited	[InstanceEdit:5671747] Orlic-Milacic, Marija, 2015-02-02
input	[Complex:5672334] RAC1,CDC42:GTP:IQGAP1 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:377732] CLIP1 [cytosol] [Homo sapiens] [Complex:190599] Microtubule [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5672327] Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170 [LiteratureReference:5672323] Regulation of lamellipodia formation and cell invasion by CLIP-170 in invasive human breast cancer cells
modified	[InstanceEdit:5674244] Orlic-Milacic, Marija, 2015-02-11 [InstanceEdit:5674558] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:8982502] Orlic-Milacic, Marija, 2017-03-18 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	IQGAP1 binds CLIP1 and microtubules
output	[Complex:5672333] RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:5626469] GTP-bound RAC1 and CDC42 bind IQGAPs [Homo sapiens] [Reaction:8848618] Activation of RAC1 by the PXN:CRK complex [Homo sapiens]
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5680200] R-HSA-5672329.3
summation	[Summation:5672330] Once bound to activated RAC1 (RAC1:GTP) or CDC42 (CDC42:GTP)...
(hasEvent)	[Pathway:5626467] RHO GTPases activate IQGAPs [Homo sapiens]
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No pathways have been reviewed or authored by IQGAP1 binds CLIP1 and microtubules (5672329)