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Details on Person Beclin-1 complex phosphorylates PtdIns

Class:Id	Reaction:5672012
_displayName	Beclin-1 complex phosphorylates PtdIns
_doRelease	TRUE
_timestamp	2020-04-02 10:38:38
authored	[InstanceEdit:5671581] Jupe, Steve, 2015-02-02
catalystActivity	[CatalystActivity:5676051] 1-phosphatidylinositol-3-kinase activity of ATG14:PIK3C3:PIK3R4:p-S15-BECN1 [endoplasmic reticulum membrane]
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:5672023] Jupe, Steve, 2015-02-04
edited	[InstanceEdit:5692984] Jupe, Steve, 2015-05-13
input	[SimpleEntity:426639] PI [endoplasmic reticulum membrane] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:1675846] A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system
modified	[InstanceEdit:5676019] Jupe, Steve, 2015-02-18 [InstanceEdit:5676050] Jupe, Steve, 2015-02-18 [InstanceEdit:5678312] Jupe, Steve, 2015-02-23 [InstanceEdit:5679261] Jupe, Steve, 2015-03-03 [InstanceEdit:5683339] Jupe, Steve, 2015-03-13 [InstanceEdit:5683719] Jupe, Steve, 2015-03-16 [InstanceEdit:5692976] Jupe, Steve, 2015-05-13 [InstanceEdit:5693009] Jupe, Steve, 2015-05-13 [InstanceEdit:6793655] Jupe, Steve, 2015-09-03 [InstanceEdit:9612935] Varusai, Thawfeek, 2018-07-05 [InstanceEdit:9638325] Varusai, Thawfeek, 2019-03-05 [InstanceEdit:9681506] Varusai, Thawfeek, 2020-04-02 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Beclin-1 complex phosphorylates PtdIns
output	[SimpleEntity:5676030] PI3P [endoplasmic reticulum membrane] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:5679205] ULK1 phosphorylates Beclin-1 [Homo sapiens] [Reaction:5679266] Beclin-1 complex translocates to the ER [Homo sapiens] [Reaction:5679239] ULK complex translocates to the ER [Homo sapiens]
releaseDate	2015-06-17
reviewed	[InstanceEdit:5693008] Tooze, Sharon A, 2015-05-13 [InstanceEdit:6793656] Klionsky, Daniel J, 2015-09-03
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:9638297] Varusai, Thawfeek, 2019-03-05
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5695714] R-HSA-5672012.6
summation	[Summation:5672016] The Beclin-1 complex (ATG14:PIK3C3:PIK3R4:BECN1) is essentia...
(hasEvent)	[Pathway:1632852] Macroautophagy [Homo sapiens]
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No pathways have been reviewed or authored by Beclin-1 complex phosphorylates PtdIns (5672012)