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Details on Person p-AMPK:AMP binds the ULK complex

Class:Id	Reaction:5672011
_displayName	p-AMPK:AMP binds the ULK complex
_doRelease	TRUE
_timestamp	2020-04-02 10:43:18
authored	[InstanceEdit:5671581] Jupe, Steve, 2015-02-02
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5672023] Jupe, Steve, 2015-02-04
edited	[InstanceEdit:5692984] Jupe, Steve, 2015-05-13
input	[Complex:380931] p-AMPK heterotrimer:AMP [cytosol] [Homo sapiens] [Complex:5666059] ULK1:ATG13:RB1CC1:ATG101 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5672825] Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
modified	[InstanceEdit:5673756] Jupe, Steve, 2015-02-10 [InstanceEdit:5675638] Jupe, Steve, 2015-02-16 [InstanceEdit:5692976] Jupe, Steve, 2015-05-13 [InstanceEdit:5693009] Jupe, Steve, 2015-05-13 [InstanceEdit:6793655] Jupe, Steve, 2015-09-03 [InstanceEdit:9638325] Varusai, Thawfeek, 2019-03-05 [InstanceEdit:9681506] Varusai, Thawfeek, 2020-04-02 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	p-AMPK:AMP binds the ULK complex
output	[Complex:5672141] p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] [Homo sapiens]
precedingEvent	[BlackBoxEvent:5683925] ULK1 is dephosphorylated [Homo sapiens] [Reaction:5675790] MTORC1 dissociates from ULK complex [Homo sapiens]
releaseDate	2015-06-17
reviewed	[InstanceEdit:5693008] Tooze, Sharon A, 2015-05-13 [InstanceEdit:6793656] Klionsky, Daniel J, 2015-09-03
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:9638297] Varusai, Thawfeek, 2019-03-05
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5695713] R-HSA-5672011.5
summation	[Summation:5672138] The heterotrimeric AMPK kinase complex, when bound to AMP, ...
(hasEvent)	[Pathway:1632852] Macroautophagy [Homo sapiens]
(precedingEvent)	[Reaction:5665868] AMPK (complex) phosphorylates ULK1 (complex) [Homo sapiens] [Reaction:5672817] Active MTORC1 binds the ULK1 complex [Homo sapiens]
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No pathways have been reviewed or authored by p-AMPK:AMP binds the ULK complex (5672011)