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Details on Person cIAP1,2:TRAF2:TRAF3:NIK [cytosol]

Class:Id	Complex:5668435
_displayName	cIAP1,2:TRAF2:TRAF3:NIK [cytosol]
_timestamp	2015-05-25 03:13:59
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5668484] Garapati, Phani Vijay, 2015-01-26
hasComponent	[Complex:5668489] TRAF2:cIAP1,2 [cytosol] [Homo sapiens] [DefinedSet:5668465] cIAP1,2 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:66370] TRAF2 [cytosol] [Homo sapiens] [Complex:5668511] TRAF3:NIK [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:914241] TRAF3 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:168189] MAP3K14 [cytosol] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:5668515] Garapati, Phani Vijay, 2015-01-26 [InstanceEdit:5668905] Garapati, Phani Vijay, 2015-01-29 [InstanceEdit:5692505] Garapati, Phani Vijay, 2015-05-12
name	cIAP1,2:TRAF2:TRAF3:NIK
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5694983] R-HSA-5668435.1
(hasComponent)	[Complex:5668447] TNFA:TNFR2 heterotrimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] [Homo sapiens] [Complex:5676555] 3xFn14:TWEAK:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] [Homo sapiens] [Complex:5676556] CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] [Homo sapiens] [Complex:5676557] 3xRANK:RANKL,sRANKL trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] [Homo sapiens] [Complex:5676558] 3xLTBR:lymphotoxin,TNFSF14 trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] [Homo sapiens] [Complex:5676561] 3xBAFFR:BAFF trimer:TRAF3:NIK [plasma membrane] [Homo sapiens]
(input)	[Reaction:5668417] cIAP1,2:TRAF2:TRAF3:NIK complex binds TNFR2 trimer [Homo sapiens] [BlackBoxEvent:5668534] cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK [Homo sapiens] [Reaction:5676593] TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR [Homo sapiens] [Reaction:5676595] TRAFs bind RANK:RANKL [Homo sapiens] [Reaction:5676596] TRAF3 binds BAFFR:BAFF [Homo sapiens] [Reaction:5676597] TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40 [Homo sapiens] [Reaction:5676598] TRAF2:cIAP1/2 complex binds FN14:TWEAK [Homo sapiens]
(output)	[Reaction:5668543] TRAF3:NIK binds TRAF2:cIAP1/2 [Homo sapiens]
(physicalEntity)	[CatalystActivity:5668529] ubiquitin-protein transferase activity of cIAP1,2:TRAF2:TRAF3:NIK [cytosol]
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No pathways have been reviewed or authored by cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (5668435)