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Details on Person DIAPH1 binds RHOA:GTP

Class:IdReaction:5665989
_displayNameDIAPH1 binds RHOA:GTP
_doReleaseTRUE
_timestamp2015-03-04 03:51:24
authored[InstanceEdit:5628889] Orlic-Milacic, Marija, 2014-10-24
[InstanceEdit:5668821] Rivero Crespo, Francisco, 2014-12-26
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:5665990] Orlic-Milacic, Marija, 2015-01-20
edited[InstanceEdit:5671747] Orlic-Milacic, Marija, 2015-02-02
input[Complex:5665993] RHOA:GTP [plasma membrane] [Homo sapiens]
[Complex:5665967] DIAPH1 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:5665985] Structural basis of Rho GTPase-mediated activation of the formin mDia1
[LiteratureReference:5665980] RhoA and DIAPH1 mediate adrenocorticotropin-stimulated cortisol biosynthesis by regulating mitochondrial trafficking
[LiteratureReference:5665994] [PI3-kinase mediates activity of RhoA and interaction of RhoA with mDia1 in thrombin-induced platelet aggregation]
modified[InstanceEdit:5674244] Orlic-Milacic, Marija, 2015-02-11
[InstanceEdit:5674560] Orlic-Milacic, Marija, 2015-02-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameDIAPH1 binds RHOA:GTP
output[Complex:5665988] RHOA:GTP:DIAPH1 [plasma membrane] [Homo sapiens]
releaseDate2015-03-19
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5679836] R-HSA-5665989.2
summation[Summation:5665991] DIAPH1 is activated by binding of the DIAPH1 dimer to GTP-bo...
(hasEvent)[Pathway:5663220] RHO GTPases Activate Formins [Homo sapiens]
(precedingEvent)[Reaction:5665982] RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 [Homo sapiens]
[Reaction:6785648] MEMO1 binds RHOA:GTP:DIAPH1 [Homo sapiens]
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No pathways have been reviewed or authored by DIAPH1 binds RHOA:GTP (5665989)