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Details on Person SRGAP2 is a GTPase activating protein that stimulates the GT...
| Class:Id | Summation:5665812 |
|---|---|
| _displayName | SRGAP2 is a GTPase activating protein that stimulates the GT... |
| _timestamp | 2015-02-06 04:40:59 |
| created | [InstanceEdit:5665811] Orlic-Milacic, Marija, 2015-01-19 |
| modified | [InstanceEdit:5672743] Orlic-Milacic, Marija, 2015-02-06 |
| text | SRGAP2 is a GTPase activating protein that stimulates the GTPase activity of RAC1 bound to FMNL1. GTP hydrolysis produces inactive GDP-bound RAC1 which is unable to bind and activate FMNL1. SRGAP2 thereby limits the duration of FMNL1-mediated elongation of actin filaments downstream of RAC1:GTP (Mason et al. 2011). |
| (summation) | [Reaction:5665809] SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments [Homo sapiens] |
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No pathways have been reviewed or authored by SRGAP2 is a GTPase activating protein that stimulates the GT... (5665812)
