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Details on Person SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane]

Class:Id	Complex:5665803
_displayName	SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane]
_timestamp	2015-03-04 05:45:02
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:5665800] Orlic-Milacic, Marija, 2015-01-19
hasComponent	[Complex:5665660] RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] [Homo sapiens] [Complex:5663231] RAC1:GTP:FMNL1 [plasma membrane] [Homo sapiens] [Complex:442641] RAC1:GTP [plasma membrane] [Homo sapiens] [SimpleEntity:29438] GTP [cytosol] [EntityWithAccessionedSequence:351141] RAC1 [plasma membrane] [Homo sapiens] [Complex:5665949] FMNL1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:5663224] FMNL1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:5663224] FMNL1 [cytosol] [Homo sapiens] [Complex:203080] Profilin:G-actin [cytosol] [Homo sapiens] [Complex:201857] G-actin [cytosol] [Homo sapiens] [DefinedSet:201859] ACTB, ACTG1 [cytosol] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol] [CandidateSet:203077] PFN [cytosol] [Homo sapiens] [Complex:203080] Profilin:G-actin [cytosol] [Homo sapiens] [Complex:201857] G-actin [cytosol] [Homo sapiens] [DefinedSet:201859] ACTB, ACTG1 [cytosol] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol] [CandidateSet:203077] PFN [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:195131] SRGAP2 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5665805] Bi-modal regulation of a formin by srGAP2
name	SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5681409] R-HSA-5665803.1
(input)	[Reaction:5665809] SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments [Homo sapiens]
(output)	[Reaction:5665802] SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin [Homo sapiens]
(physicalEntity)	[CatalystActivity:5665807] GTPase activity of SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane]
(updatedInstance)	[_UpdateTracker:9897732] Update Tracker - [Complex:5665803] SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] - v62:[updateContainedComponent] [_UpdateTracker:9972734] Update Tracker - [Complex:5665803] SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] - v95:[updateContainedComponent]
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No pathways have been reviewed or authored by SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (5665803)