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Details on Person RORA and EP300 bind NPAS2 gene

Class:Id	Reaction:5663246
_displayName	RORA and EP300 bind NPAS2 gene
_doRelease	TRUE
_timestamp	2025-02-19 18:26:44
authored	[InstanceEdit:5663195] May, Bruce, 2015-01-15
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5663250] May, Bruce, 2015-01-16
edited	[InstanceEdit:5663195] May, Bruce, 2015-01-15
inferredFrom	[Reaction:5663256] Rora and Ep300 bind Npas2 gene [Mus musculus]
input	[EntityWithAccessionedSequence:381325] EP300 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:400325] RORA [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:5640176] NPAS2 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5669329] Nuclear receptor-mediated cell-autonomous oscillatory expression of the circadian transcription factor, neuronal PAS domain protein 2 (NPAS2)
modified	[InstanceEdit:5663298] May, Bruce, 2015-01-17 [InstanceEdit:5663310] May, Bruce, 2015-01-17 [InstanceEdit:5663311] May, Bruce, 2015-01-17 [InstanceEdit:5669335] May, Bruce, 2015-02-02 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9935064] May, Bruce, 2025-01-12 [InstanceEdit:9936865] May, Bruce, 2025-01-27 [InstanceEdit:9938391] May, Bruce, 2025-02-14 [InstanceEdit:9938697] May, Bruce, 2025-02-18 [InstanceEdit:9938770] May, Bruce, 2025-02-19
name	RORA and EP300 bind NPAS2 gene
output	[Complex:5663257] RORA:EP300:NPAS2 gene [nucleoplasm] [Homo sapiens]
releaseDate	2015-03-19
reviewed	[InstanceEdit:2084235] Delaunay, F, 2012-01-28 [InstanceEdit:9938389] Sancar, Aziz, 2025-02-14 [InstanceEdit:9938694] Albrecht, Urs, 2025-02-18
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5680315] R-HSA-5663246.3
summation	[Summation:1801579] ROR-alpha (RORA) binds the promoter of the NPAS2 gene and en...
(hasEvent)	[Pathway:9931509] Expression of BMAL (ARNTL), CLOCK, and NPAS2 [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:1368065] RORA and PPARA positively regulate and NR1D1 negatively regulates expression of NPAS2 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9939752] Update Tracker - [Reaction:5663246] RORA and EP300 bind NPAS2 gene - v92:[modifyText]
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No pathways have been reviewed or authored by RORA and EP300 bind NPAS2 gene (5663246)