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Details on Person p-S90-BMAL1:p-T451,T461-CLOCK binds PPARA gene

Class:Id	Reaction:5663156
_displayName	p-S90-BMAL1:p-T451,T461-CLOCK binds PPARA gene
_doRelease	TRUE
_timestamp	2025-06-02 14:50:09
authored	[InstanceEdit:5663109] May, Bruce, 2015-01-14
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5663103] May, Bruce, 2015-01-15
edited	[InstanceEdit:5663109] May, Bruce, 2015-01-14
inferredFrom	[Reaction:5663129] p-S97-Bmal1:p-T451,T461-Clock binds Ppara gene [Mus musculus]
input	[EntityWithAccessionedSequence:5640195] PPARA gene [nucleoplasm] [Homo sapiens] [Complex:9920661] p-S90-BMAL1:p-T451,T461-CLOCK [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:879721] CLOCK is involved in the circadian transactivation of peroxisome-proliferator-activated receptor alpha (PPARalpha) in mice
modified	[InstanceEdit:5663310] May, Bruce, 2015-01-17 [InstanceEdit:5663311] May, Bruce, 2015-01-17 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9938714] May, Bruce, 2025-02-18 [InstanceEdit:9938770] May, Bruce, 2025-02-19 [InstanceEdit:9940986] May, Bruce, 2025-03-06 [InstanceEdit:9953423] May, Bruce, 2025-06-02
name	p-S90-BMAL1:p-T451,T461-CLOCK binds PPARA gene
output	[Complex:5663137] p-S90-BMAL1:p-T451,T461-CLOCK:PPARA gene [nucleoplasm] [Homo sapiens]
precedingEvent	[BlackBoxEvent:9920665] p-S90-BMAL1:p-T451,T461-CLOCK translocates from the cytosol to the nucleus [Homo sapiens] [Reaction:9912390] p-S90-BMAL1 binds p-T451,T461-CLOCK [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821384] two stars
releaseDate	2015-03-19
reviewed	[InstanceEdit:879756] Albrecht, Urs, 2010-06-23 [InstanceEdit:422151] D'Eustachio, P, 2009-05-26 22:13:22 [InstanceEdit:879786] Delaunay, F, 2010-06-23 [InstanceEdit:879790] Hirota, T, 2010-06-23 [InstanceEdit:879726] Kay, SA, 2010-06-23 [InstanceEdit:9953422] Albrecht, Urs, 2025-03-07
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5680063] R-HSA-5663156.4
structureModified	[InstanceEdit:9940986] May, Bruce, 2025-03-06
summation	[Summation:879845] As inferred from mouse, BMAL1:CLOCK (ARNTL:CLOCK) heterodime...
(hasEvent)	[Pathway:1368108] BMAL1:CLOCK,NPAS2 activates circadian expression [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:879724] Expression of PPARA [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9953687] Update Tracker - [Reaction:5663156] p-S90-BMAL1:p-T451,T461-CLOCK binds PPARA gene - v93:[add_removeInput]
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No pathways have been reviewed or authored by p-S90-BMAL1:p-T451,T461-CLOCK binds PPARA gene (5663156)