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Details on Person MT2A binds copper

Class:Id	Reaction:5662986
_displayName	MT2A binds copper
_doRelease	TRUE
_timestamp	2016-03-12 07:45:28
authored	[InstanceEdit:5662654] May, Bruce, 2015-01-12
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5662993] May, Bruce, 2015-01-14
edited	[InstanceEdit:5662654] May, Bruce, 2015-01-12
input	[EntityWithAccessionedSequence:1031707] MT2A [cytosol] [Homo sapiens] [SimpleEntity:3299744] Cu1+ [cytosol] [SimpleEntity:3299744] Cu1+ [cytosol] [SimpleEntity:3299744] Cu1+ [cytosol] [SimpleEntity:3299744] Cu1+ [cytosol] [SimpleEntity:3299744] Cu1+ [cytosol] [SimpleEntity:3299744] Cu1+ [cytosol] [SimpleEntity:3299744] Cu1+ [cytosol] [SimpleEntity:3299744] Cu1+ [cytosol] [SimpleEntity:3299744] Cu1+ [cytosol] [SimpleEntity:3299744] Cu1+ [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:5662982] The native copper- and zinc-binding protein metallothionein blocks copper-mediated Abeta aggregation and toxicity in rat cortical neurons [LiteratureReference:5662989] Affinity gradients drive copper to cellular destinations
modified	[InstanceEdit:5683530] May, Bruce, 2015-03-15 [InstanceEdit:5690961] May, Bruce, 2015-05-02 [InstanceEdit:6798594] May, Bruce, 2015-09-19 [InstanceEdit:6814143] May, Bruce, 2015-11-25 [InstanceEdit:8864144] May, Bruce, 2016-03-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MT2A binds copper
output	[Complex:5662969] MT2A:10Cu1+ [cytosol] [Homo sapiens]
precedingEvent	[BlackBoxEvent:5660483] Expression of MT2A [Homo sapiens] [Reaction:5660495] MTF1 dimer:12Zn2+ binds MT2A gene [Homo sapiens]
releaseDate	2015-12-15
releaseStatus	NEW
reviewed	[InstanceEdit:6798577] Atrian, S�lvia, 2015-09-19
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6812396] R-HSA-5662986.4
summation	[Summation:5683448] The metallothionein MT2A binds 10 atoms of copper(I). Comple...
(hasEvent)	[Pathway:5661231] Metallothioneins bind metals [Homo sapiens]
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No pathways have been reviewed or authored by MT2A binds copper (5662986)