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Details on Person Expression of SLC30A2

Class:Id	BlackBoxEvent:5662616
_displayName	Expression of SLC30A2
_timestamp	2018-10-31 14:35:33
authored	[InstanceEdit:5661316] May, Bruce, 2015-01-09
compartment	[Compartment:7660] nucleoplasm [Compartment:74700] endosome membrane
created	[InstanceEdit:5662602] May, Bruce, 2015-01-12
edited	[InstanceEdit:5661316] May, Bruce, 2015-01-09
input	[EntityWithAccessionedSequence:5662588] SLC30A2 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5674910] Coordinative modulation of human zinc transporter 2 gene expression through active and suppressive regulators [LiteratureReference:5674781] Zinc transporter-2 (ZnT2) variants are localized to distinct subcellular compartments and functionally transport zinc [LiteratureReference:5674705] Expression of ZnT and ZIP zinc transporters in the human RPE and their regulation by neurotrophic factors
modified	[InstanceEdit:5674976] May, Bruce, 2015-02-14 [InstanceEdit:5676005] May, Bruce, 2015-02-18 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9627001] May, Bruce, 2018-10-31 [InstanceEdit:9641190] Wu, G, 2019-04-04
name	Expression of SLC30A2
output	[EntityWithAccessionedSequence:435363] SLC30A2 [endosome membrane] [Homo sapiens]
precedingEvent	[Reaction:5662600] MTF1 dimer:12Zn2+ binds SLC30A2 gene [Homo sapiens] [BlackBoxEvent:5660525] MTF1 dimer:12Zn2+ translocates from cytosol to nucleus [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:5662630] Positive gene expression regulation by 'MTF1 dimer:12Zn2+:SLC30A2 gene [nucleoplasm]'
regulationReference	[RegulationReference:9642475] Positive gene expression regulation by 'MTF1 dimer:12Zn2+:SLC30A2 gene [nucleoplasm]' STAT5-glucocorticoid receptor interaction and MTF-1 regulate the expression of ZnT2 (Slc30a2) in pancreatic acinar cells
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8897544] R-HSA-5662616.1
summation	[Summation:5675999] The SLC30A2 (ZnT2) gene is transcribed to yield mRNA which i...
(hasEvent)	[Pathway:5660489] MTF1 activates gene expression [Homo sapiens]
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No pathways have been reviewed or authored by Expression of SLC30A2 (5662616)