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Details on Person SORD tetramer oxidizes xylitol to D-xylulose

Class:IdReaction:5662471
_displayNameSORD tetramer oxidizes xylitol to D-xylulose
_doReleaseTRUE
_timestamp2015-09-04 20:31:12
authored[InstanceEdit:6790587] D'Eustachio, Peter, 2015-08-13
catalystActivity[CatalystActivity:5661275] D-xylulose reductase activity of SORD tetramer [cytosol]
catalystActivityReference[CatalystActivityReference:9643789] D-xylulose reductase activity of SORD tetramer [cytosol] Membrane-bound sorbitol dehydrogenase in human red blood cells. Studies in normal subjects and in enzyme-deficient subjects with congenital cataracts
compartment[Compartment:70101] cytosol
created[InstanceEdit:5662467] D'Eustachio, Peter, 2015-01-12
edited[InstanceEdit:6790587] D'Eustachio, Peter, 2015-08-13
input[SimpleEntity:5660033] xylitol [cytosol]
[SimpleEntity:29360] NAD+ [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:5661252] Membrane-bound sorbitol dehydrogenase in human red blood cells. Studies in normal subjects and in enzyme-deficient subjects with congenital cataracts
[LiteratureReference:5652208] Variability within mammalian sorbitol dehydrogenases. The primary structure of the human liver enzyme
[LiteratureReference:5662470] Purification and characterization of human liver sorbitol dehydrogenase
[LiteratureReference:5652201] X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase
modified[InstanceEdit:5662474] D'Eustachio, Peter, 2015-01-12
[InstanceEdit:5668911] Jassal, Bijay, 2015-01-29
[InstanceEdit:5668965] D'Eustachio, Peter, 2015-01-29
[InstanceEdit:5674544] D'Eustachio, Peter, 2015-02-12
[InstanceEdit:5678587] D'Eustachio, Peter, 2015-02-24
[InstanceEdit:6790585] D'Eustachio, Peter, 2015-08-13
[InstanceEdit:6793056] D'Eustachio, Peter, 2015-08-28
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameSORD tetramer oxidizes xylitol to D-xylulose
xylitol + NAD+ => D-xylulose + NADH + H+
output[SimpleEntity:5661281] D-xylulose [cytosol]
[SimpleEntity:73473] NADH [cytosol]
[SimpleEntity:70106] H+ [cytosol]
precedingEvent
releaseDate2015-09-22
releaseStatusNEW
reviewed[InstanceEdit:6790586] Jassal, Bijay, 2015-08-13
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:6796668] R-HSA-5662471.3
summation[Summation:5662465] Tetrameric sorbitol dehydrogenase (SORD tetramer) catalyzes ...
(hasEvent)[Pathway:5661270] Formation of xylulose-5-phosphate [Homo sapiens]
(precedingEvent)[Reaction:5662466] XYLB phosphorylates D-xylulose [Homo sapiens]
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