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Details on Person Expression of MT3

Class:IdBlackBoxEvent:5661308
_displayNameExpression of MT3
_timestamp2018-10-31 14:18:23
authored[InstanceEdit:5661239] May, Bruce, 2015-01-09
compartment[Compartment:7660] nucleoplasm
[Compartment:70101] cytosol
created[InstanceEdit:5661311] May, Bruce, 2015-01-09
edited[InstanceEdit:5661239] May, Bruce, 2015-01-09
input[EntityWithAccessionedSequence:5661313] MT3 gene [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:5674894] Metallothionein gene expression is altered in oral cancer and may predict metastasis and patient outcomes
[LiteratureReference:5674707] Expression, regulation and function of human metallothioneins in endothelial cells
[LiteratureReference:5674927] Metallothionein 3: an androgen-upregulated gene enhances cell invasion and tumorigenesis of prostate carcinoma cells
[LiteratureReference:5674641] Expression of metallothionein-III in patients with non-small cell lung cancer
[LiteratureReference:5674796] Differential expression of metallothioneins (MTs) 1, 2, and 3 in response to zinc treatment in human prostate normal and malignant cells and tissues
[LiteratureReference:5674645] PCR arrays identify metallothionein-3 as a highly hypoxia-inducible gene in human adipocytes
[LiteratureReference:5674640] Metallothionein isoform 3 and proximal tubule vectorial active transport
[LiteratureReference:5674712] Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes
[LiteratureReference:5674790] Differences in the epigenetic regulation of MT-3 gene expression between parental and Cd+2 or As+3 transformed human urothelial cells
[LiteratureReference:5660248] Gains, losses and changes of function after gene duplication: study of the metallothionein family
[LiteratureReference:5690964] Metallothionein isoform 3 expression in human skin, related cancers and human skin derived cell cultures
modified[InstanceEdit:5674976] May, Bruce, 2015-02-14
[InstanceEdit:5675919] May, Bruce, 2015-02-18
[InstanceEdit:5690965] May, Bruce, 2015-05-03
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9626996] May, Bruce, 2018-10-31
[InstanceEdit:9641190] Wu, G, 2019-04-04
[InstanceEdit:9733355] Wu, Guanming, 2021-06-04
nameExpression of MT3
output[EntityWithAccessionedSequence:5660396] MT3 [cytosol] [Homo sapiens]
precedingEvent
regulatedBy[PositiveGeneExpressionRegulation:5684738] Positive gene expression regulation by 'MTF1 dimer:12Zn2+:MT3 gene [nucleoplasm]'
regulationReference[RegulationReference:9641590] Positive gene expression regulation by 'MTF1 dimer:12Zn2+:MT3 gene [nucleoplasm]' Trace element status and zinc homeostasis differ in breast and formula-fed piglets
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8896136] R-HSA-5661308.1
summation[Summation:5674977] The MT3 gene is transcribed to yield mRNA which is translate...
[Summation:5684755] As inferred from pig homologs (Ronis et al. 2015) and comput...
(hasEvent)[Pathway:5660489] MTF1 activates gene expression [Homo sapiens]
(precedingEvent)[Reaction:5662606] MT3 binds zinc [Homo sapiens]
[Reaction:5662620] MT3 binds cadmium [Homo sapiens]
[Reaction:5663002] MT3 binds copper [Homo sapiens]
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No pathways have been reviewed or authored by Expression of MT3 (5661308)