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Details on Person Expression of MT1H

Class:IdBlackBoxEvent:5661297
_displayNameExpression of MT1H
_timestamp2018-10-31 14:16:54
authored[InstanceEdit:5661239] May, Bruce, 2015-01-09
compartment[Compartment:7660] nucleoplasm
[Compartment:70101] cytosol
created[InstanceEdit:5661311] May, Bruce, 2015-01-09
edited[InstanceEdit:5661239] May, Bruce, 2015-01-09
input[EntityWithAccessionedSequence:5661294] MT1H gene [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:5660206] Extremely low copper concentrations affect gene expression profiles of human prostate epithelial cell lines
[LiteratureReference:5674858] Up-regulation of metallothionein gene expression in parkinsonian astrocytes
[LiteratureReference:5674684] Characterisation of six additional human metallothionein genes
[LiteratureReference:5674712] Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes
[LiteratureReference:5660248] Gains, losses and changes of function after gene duplication: study of the metallothionein family
[LiteratureReference:8954367] Zinc sensing by metal-responsive transcription factor 1 (MTF1) controls metallothionein and ZnT1 expression to buffer the sensitivity of the transcriptome response to zinc
modified[InstanceEdit:5674976] May, Bruce, 2015-02-14
[InstanceEdit:5675919] May, Bruce, 2015-02-18
[InstanceEdit:5676005] May, Bruce, 2015-02-18
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:8954377] May, Bruce, 2017-01-07
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9626996] May, Bruce, 2018-10-31
[InstanceEdit:9641190] Wu, G, 2019-04-04
[InstanceEdit:9733355] Wu, Guanming, 2021-06-04
nameExpression of MT1H
output[EntityWithAccessionedSequence:5661218] MT1H [cytosol] [Homo sapiens]
precedingEvent
regulatedBy[PositiveGeneExpressionRegulation:5684740] Positive gene expression regulation by 'MTF1 dimer:12Zn2+:MT1H gene [nucleoplasm]'
regulationReference[RegulationReference:9642022] Positive gene expression regulation by 'MTF1 dimer:12Zn2+:MT1H gene [nucleoplasm]' Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8885726] R-HSA-5661297.1
summation[Summation:5675994] The MT1H gene is transcribed to yield mRNA which is translat...
[Summation:5684762] As inferred from the induction of MT1H by zinc (Vandeghinst...
(hasEvent)[Pathway:5660489] MTF1 activates gene expression [Homo sapiens]
(precedingEvent)[Reaction:5662597] MT1H binds cadmium [Homo sapiens]
[Reaction:5662619] MT1H binds zinc [Homo sapiens]
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