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Details on Person AKR1A1 reduces D-glucuronate to L-gulonate

Class:Id	Reaction:5661256
_displayName	AKR1A1 reduces D-glucuronate to L-gulonate
_doRelease	TRUE
_timestamp	2015-09-04 20:31:09
authored	[InstanceEdit:6790587] D'Eustachio, Peter, 2015-08-13
catalystActivity	[CatalystActivity:5661271] L-glucuronate reductase activity of AKR1A1 [cytosol]
catalystActivityReference	[CatalystActivityReference:9643270] L-glucuronate reductase activity of AKR1A1 [cytosol] Mechanism of human aldehyde reductase: characterization of the active site pocket
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5661263] D'Eustachio, Peter, 2015-01-09
edited	[InstanceEdit:6790587] D'Eustachio, Peter, 2015-08-13
input	[SimpleEntity:5661264] D-glucuronate [cytosol] [SimpleEntity:29364] NADPH [cytosol] [SimpleEntity:70106] H+ [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:5661283] Mechanism of human aldehyde reductase: characterization of the active site pocket
modified	[InstanceEdit:5668965] D'Eustachio, Peter, 2015-01-29 [InstanceEdit:5674544] D'Eustachio, Peter, 2015-02-12 [InstanceEdit:5678341] Jassal, Bijay, 2015-02-23 [InstanceEdit:5678587] D'Eustachio, Peter, 2015-02-24 [InstanceEdit:6790585] D'Eustachio, Peter, 2015-08-13 [InstanceEdit:6793056] D'Eustachio, Peter, 2015-08-28 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	AKR1A1 reduces D-glucuronate to L-gulonate D-glucuronate + NADPH + H+ => L-gulonate + NADP+
output	[SimpleEntity:5661268] L-gulonate [cytosol] [SimpleEntity:29366] NADP+ [cytosol]
releaseDate	2015-09-22
releaseStatus	NEW
reviewed	[InstanceEdit:6790586] Jassal, Bijay, 2015-08-13
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6796664] R-HSA-5661256.3
summation	[Summation:5661265] Cytosolic AKR1A1 (Aldo-keto reductase family 1 member A1) ca...
(hasEvent)	[Pathway:5661270] Formation of xylulose-5-phosphate [Homo sapiens]
(precedingEvent)	[Reaction:5661290] CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate [Homo sapiens]
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No pathways have been reviewed or authored by AKR1A1 reduces D-glucuronate to L-gulonate (5661256)