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Details on Person DCXR tetramer reduces L-xylulose to xylitol
Class:Id Reaction:5661240 _displayName DCXR tetramer reduces L-xylulose to xylitol _doRelease TRUE _timestamp 2015-09-04 20:31:08 authored [InstanceEdit:6790587] D'Eustachio, Peter, 2015-08-13 catalystActivity [CatalystActivity:5660042] L-xylulose reductase (NADPH) activity of DCXR tetramer [plasma membrane] catalystActivityReference [CatalystActivityReference:9643179] L-xylulose reductase (NADP+) activity of DCXR tetramer [plasma membrane] Molecular characterization of mammalian dicarbonyl/L-xylulose reductase and its localization in kidney compartment [Compartment:70101] cytosol [Compartment:876] plasma membrane created [InstanceEdit:5661241] D'Eustachio, Peter, 2015-01-09 edited [InstanceEdit:6790587] D'Eustachio, Peter, 2015-08-13 input [SimpleEntity:5660036] L-xylulose [cytosol] [SimpleEntity:29364] NADPH [cytosol] [SimpleEntity:70106] H+ [cytosol] isChimeric FALSE literatureReference [LiteratureReference:5660063] Surface localization of P34H an epididymal protein, during maturation, capacitation, and acrosome reaction of human spermatozoa [LiteratureReference:5660052] Crystal structure of human L-xylulose reductase holoenzyme: probing the role of Asn107 with site-directed mutagenesis [LiteratureReference:5660048] Molecular characterization of mammalian dicarbonyl/L-xylulose reductase and its localization in kidney [LiteratureReference:5660062] Garrod's fourth inborn error of metabolism solved by the identification of mutations causing pentosuria [LiteratureReference:5660043] The enzymatic defect in essential pentosuria modified [InstanceEdit:5661263] D'Eustachio, Peter, 2015-01-09 [InstanceEdit:5662467] D'Eustachio, Peter, 2015-01-12 [InstanceEdit:5662799] D'Eustachio, Peter, 2015-01-13 [InstanceEdit:5668911] Jassal, Bijay, 2015-01-29 [InstanceEdit:5668965] D'Eustachio, Peter, 2015-01-29 [InstanceEdit:5674544] D'Eustachio, Peter, 2015-02-12 [InstanceEdit:5678587] D'Eustachio, Peter, 2015-02-24 [InstanceEdit:6790585] D'Eustachio, Peter, 2015-08-13 [InstanceEdit:6793056] D'Eustachio, Peter, 2015-08-28 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 name DCXR tetramer reduces L-xylulose to xylitol output [SimpleEntity:5660033] xylitol [cytosol] [SimpleEntity:29366] NADP+ [cytosol] precedingEvent
releaseDate 2015-09-22 releaseStatus NEW reviewed [InstanceEdit:6790586] Jassal, Bijay, 2015-08-13 reviewStatus [ReviewStatus:9821382] five stars species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:6796659] R-HSA-5661240.3 summation [Summation:5661243] L-xylulose reductase (DCXR, also known as dicarbonyl/L-xylul... (hasEvent) [Pathway:5661270] Formation of xylulose-5-phosphate [Homo sapiens] (normalReaction) [FailedReaction:5662851] Defective DCXR does not reduce L-xylulose to xylitol [Homo sapiens] (precedingEvent) [Reaction:5662471] SORD tetramer oxidizes xylitol to D-xylulose [Homo sapiens]
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