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Details on Person Ub-SNCA dissociates from the conjugating enzyme

Class:Id	BlackBoxEvent:5660757
_displayName	Ub-SNCA dissociates from the conjugating enzyme
_doRelease	TRUE
_timestamp	2015-11-20 15:12:11
authored	[InstanceEdit:5660750] Jupe, Steve, 2015-01-06
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5660750] Jupe, Steve, 2015-01-06
edited	[InstanceEdit:6808310] Jupe, Steve, 2015-11-04
input	[Complex:5660743] SIAH1:UBE2L6:Ub-SNCA [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5660751] Monoubiquitylation of alpha-synuclein by seven in absentia homolog (SIAH) promotes its aggregation in dopaminergic cells [LiteratureReference:5660761] Protein monoubiquitination and polyubiquitination generate structural diversity to control distinct biological processes
modified	[InstanceEdit:5685190] Jupe, Steve, 2015-03-26 [InstanceEdit:6786471] Jupe, Steve, 2015-07-08 [InstanceEdit:6809158] Jupe, Steve, 2015-11-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Ub-SNCA dissociates from the conjugating enzyme
output	[EntityWithAccessionedSequence:374563] SIAH1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:5660754] Ub-SNCA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:936014] UBE2L6 [cytosol] [Homo sapiens]
precedingEvent	[Reaction:5660753] SIAH1:UBE2L6:Ubiquitin ubiquitinates SNCA [Homo sapiens] [Reaction:5658496] SIAH1:UBE2L6:Ubiquitin binds SNCA [Homo sapiens]
releaseDate	2015-12-15
releaseStatus	NEW
reviewed	[InstanceEdit:6809157] Perry, George, 2015-11-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6812607] R-HSA-5660757.2
summation	[Summation:5660741] SNCA is monoubiquitinated and under some circumstances relea...
(hasEvent)	[Pathway:977225] Amyloid fiber formation [Homo sapiens]
(precedingEvent)	[Reaction:5661157] USP9X binds Ub-SNCA [Homo sapiens]
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No pathways have been reviewed or authored by Ub-SNCA dissociates from the conjugating enzyme (5660757)