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Details on Person ASC binds Caspase-8 complex

Class:Id	Reaction:5660662
_displayName	ASC binds Caspase-8 complex
_doRelease	TRUE
_timestamp	2015-03-04 04:21:27
authored	[InstanceEdit:5660664] Garapati, P V, 2015-01-04
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5660664] Garapati, P V, 2015-01-04
edited	[InstanceEdit:5660664] Garapati, P V, 2015-01-04
input	[Complex:5660654] MALT1:active caspase-8 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:561191] PYCARD [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5660631] ASC is an activating adaptor for NF-kappa B and caspase-8-dependent apoptosis [LiteratureReference:5660611] Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1? via a noncanonical caspase-8 inflammasome
modified	[InstanceEdit:5660673] Garapati, P V, 2015-01-05 [InstanceEdit:5663069] Garapati, P V, 2015-01-15 [InstanceEdit:5674203] Garapati, P V, 2015-02-11 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ASC binds Caspase-8 complex
output	[Complex:5660653] MALT1 oligomers:active caspase-8:ASC [cytosol] [Homo sapiens]
precedingEvent	[Reaction:5660665] Caspase-8 binds MALT [Homo sapiens]
releaseDate	2015-03-19
reviewed	[InstanceEdit:5621625] Geijtenbeek, Teunis B H, 2014-09-02
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5680351] R-HSA-5660662.2
summation	[Summation:5660588] ASC (adaptor protein apoptosis-associated speck-like protein...
(hasEvent)	[Pathway:5660668] CLEC7A/inflammasome pathway [Homo sapiens]
(precedingEvent)	[Reaction:5660663] Caspase-8 cleaves IL1B precursor [Homo sapiens]
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No pathways have been reviewed or authored by ASC binds Caspase-8 complex (5660662)