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Details on Person Expression of SLC30A1 (ZnT1)

Class:Id	BlackBoxEvent:5660502
_displayName	Expression of SLC30A1 (ZnT1)
_timestamp	2018-10-31 14:35:19
authored	[InstanceEdit:5660523] May, Bruce, 2014-12-27
compartment	[Compartment:7660] nucleoplasm [Compartment:876] plasma membrane
created	[InstanceEdit:5660497] May, Bruce, 2015-01-04
edited	[InstanceEdit:5660523] May, Bruce, 2014-12-27
input	[EntityWithAccessionedSequence:5660416] SLC30A1 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5660327] PTEN interacts with metal-responsive transcription factor 1 and stimulates its transcriptional activity [LiteratureReference:5660214] Chromium(VI) down-regulates heavy metal-induced metallothionein gene transcription by modifying transactivation potential of the key transcription factor, metal-responsive transcription factor 1 [LiteratureReference:5660251] Zn-responsive proteome profiling and time-dependent expression of proteins regulated by MTF-1 in A549 cells
modified	[InstanceEdit:5676005] May, Bruce, 2015-02-18 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9627001] May, Bruce, 2018-10-31 [InstanceEdit:9641190] Wu, G, 2019-04-04
name	Expression of SLC30A1 (ZnT1)
output	[EntityWithAccessionedSequence:435361] SLC30A1 [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:5660515] MTF1 dimer:12Zn2+ binds SLC30A1 gene [Homo sapiens] [BlackBoxEvent:5660525] MTF1 dimer:12Zn2+ translocates from cytosol to nucleus [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:5660553] Positive gene expression regulation by 'MTF1 dimer:12Zn2+:SLC30A1 gene [nucleoplasm]'
regulationReference	[RegulationReference:9642526] Positive gene expression regulation by 'MTF1 dimer:12Zn2+:SLC30A1 gene [nucleoplasm]' PTEN interacts with metal-responsive transcription factor 1 and stimulates its transcriptional activity
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8881978] R-HSA-5660502.1
summation	[Summation:5675996] The SLC30A1 (ZnT1) gene is transcribed to yield mRNA which i...
(hasEvent)	[Pathway:5660489] MTF1 activates gene expression [Homo sapiens]
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No pathways have been reviewed or authored by Expression of SLC30A1 (ZnT1) (5660502)