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Details on Person MTF1 dimer:12Zn2+ binds SNCB gene (beta-synuclein)

Class:Id	Reaction:5660479
_displayName	MTF1 dimer:12Zn2+ binds SNCB gene (beta-synuclein)
_doRelease	TRUE
_timestamp	2017-01-11 19:13:50
authored	[InstanceEdit:5660523] May, Bruce, 2014-12-27
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5660497] May, Bruce, 2015-01-04
edited	[InstanceEdit:5660523] May, Bruce, 2014-12-27
input	[EntityWithAccessionedSequence:5660406] SNCB gene [nucleoplasm] [Homo sapiens] [Complex:5660456] MTF1 dimer:12Zn2+ [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5660170] Transcriptional regulation of the beta-synuclein 5'-promoter metal response element by metal transcription factor-1
modified	[InstanceEdit:5676005] May, Bruce, 2015-02-18 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8955433] May, Bruce, 2017-01-11 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MTF1 dimer:12Zn2+ binds SNCB gene (beta-synuclein)
output	[Complex:5660451] MTF1 dimer:12Zn2+:SNCB gene [nucleoplasm] [Homo sapiens]
precedingEvent	[BlackBoxEvent:5660525] MTF1 dimer:12Zn2+ translocates from cytosol to nucleus [Homo sapiens] [Reaction:5660494] MTF1 dimer binds zinc [Homo sapiens]
releaseDate	2017-03-27
reviewed	[InstanceEdit:8955431] Brown, David R, 2017-01-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8900507] R-HSA-5660479.2
summation	[Summation:5676002] The MTF1:zinc complex binds a metal response element in the ...
(hasEvent)	[Pathway:5660489] MTF1 activates gene expression [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:5660530] Expression of SNCB [Homo sapiens]
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No pathways have been reviewed or authored by MTF1 dimer:12Zn2+ binds SNCB gene (beta-synuclein) (5660479)