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Details on Person Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure

Class:IdLiteratureReference:5660313
_displayNameInhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure
_timestamp2015-01-04 22:18:38
author[Person:5219054] Ghoshal, Kalpana
[Person:5219069] Datta, Jharna
[Person:5219062] Majumder, Sarmila
[Person:5219056] Bai, Shoumei
[Person:5660217] Dong, Xiaocheng
[Person:5660198] Parthun, Mark
[Person:5211310] Jacob, Samson T
created[InstanceEdit:5660151] May, Bruce, 2015-01-04
journalMol. Cell. Biol.
pages8302-19
pubMedIdentifier12417732
titleInhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure
volume22
year2002
(literatureReference)[RegulationReference:9641235] Positive regulation by 'Mtf1 dimer:12Zn2+:Ep300:Sp1:Nfi dimer:Mt1 gene [nucleoplasm]' Hypoxia acts through multiple signaling pathways to induce metallothionein transactivation by the metal-responsive transcription factor-1 (MTF-1)
[BlackBoxEvent:5660476] Expression of Mt1 [Mus musculus]
[Reaction:5660505] Mtf1 dimer:12Zn2+, Sp1, Ep300, and Nfi dimer bind Mt1 gene [Mus musculus]
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No pathways have been reviewed or authored by Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure (5660313)