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Details on Person Putative zinc-sensing zinc fingers of metal-response element-binding transcription factor-1 stabilize a metal-dependent chromatin complex on the endogenous metallothionein-I promoter

Class:IdLiteratureReference:5660182
_displayNamePutative zinc-sensing zinc fingers of metal-response element-binding transcription factor-1 stabilize a metal-dependent chromatin complex on the endogenous metallothionein-I promoter
_timestamp2015-01-04 22:17:57
author[Person:5660200] Jiang, Huimin
[Person:5660230] Daniels, Patrick J
[Person:5660265] Andrews, Glen K
created[InstanceEdit:5660151] May, Bruce, 2015-01-04
journalJ. Biol. Chem.
pages30394-402
pubMedIdentifier12764133
titlePutative zinc-sensing zinc fingers of metal-response element-binding transcription factor-1 stabilize a metal-dependent chromatin complex on the endogenous metallothionein-I promoter
volume278
year2003
(literatureReference)[BlackBoxEvent:5660476] Expression of Mt1 [Mus musculus]
[BlackBoxEvent:5660482] Mtf1 dimer:12Zn2+ translocates from cytosol to nucleus [Mus musculus]
[Reaction:5660505] Mtf1 dimer:12Zn2+, Sp1, Ep300, and Nfi dimer bind Mt1 gene [Mus musculus]
[RegulationReference:9641235] Positive regulation by 'Mtf1 dimer:12Zn2+:Ep300:Sp1:Nfi dimer:Mt1 gene [nucleoplasm]' Hypoxia acts through multiple signaling pathways to induce metallothionein transactivation by the metal-responsive transcription factor-1 (MTF-1)
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