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Details on Person Defective RPIA does not isomerize R5P to RU5P

Class:IdFailedReaction:5660015
_displayNameDefective RPIA does not isomerize R5P to RU5P
_doReleaseTRUE
_timestamp2015-09-04 20:51:07
authored[InstanceEdit:5678586] D'Eustachio, Peter, 2015-02-24
catalystActivity[CatalystActivity:9631939] ribose-5-phosphate isomerase activity of RPIA A61V [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:5660012] D'Eustachio, Peter, 2015-01-03
disease[Disease:5656463] carbohydrate metabolic disorder
edited[InstanceEdit:5678586] D'Eustachio, Peter, 2015-02-24
entityFunctionalStatus[EntityFunctionalStatus:5660010] loss_of_function of RPIA A61V [cytosol]
input[SimpleEntity:73578] R5P [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:177786] Ribose-5-phosphate isomerase deficiency: new inborn error in the pentose phosphate pathway associated with a slowly progressive leukoencephalopathy
modified[InstanceEdit:5660017] D'Eustachio, Peter, 2015-01-03
[InstanceEdit:5668911] Jassal, Bijay, 2015-01-29
[InstanceEdit:5668962] D'Eustachio, Peter, 2015-01-29
[InstanceEdit:5674549] D'Eustachio, Peter, 2015-02-12
[InstanceEdit:5678295] D'Eustachio, Peter, 2015-02-23
[InstanceEdit:5678586] D'Eustachio, Peter, 2015-02-24
[InstanceEdit:6791058] D'Eustachio, Peter, 2015-08-18
[InstanceEdit:9631717] Wu, G, 2018-12-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameDefective RPIA does not isomerize R5P to RU5P
normalReaction
releaseDate2015-09-22
releaseStatusNEW
reviewed[InstanceEdit:6791056] Jassal, Bijay, 2015-08-18
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:6797180] R-HSA-5660015.3
summation[Summation:5660014] A missense mutant form of RPIA (ribose 5-phosphate isomerase...
(hasEvent)[Pathway:5659996] RPIA deficiency: failed conversion of R5P to RU5P [Homo sapiens]
(updatedInstance)[_UpdateTracker:9778132] Update Tracker - [FailedReaction:5660015] Defective RPIA does not isomerize R5P to RU5P - v68:[addCatalystActivity]
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