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Details on Person Defective SLC5A1 does not cotransport Glc and Na+
| Class:Id | FailedReaction:5656356 |
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| _displayName | Defective SLC5A1 does not cotransport Glc and Na+ |
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| _doRelease | TRUE |
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| _timestamp | 2018-11-08 19:29:07 |
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| authored | [InstanceEdit:5656371] Jassal, Bijay, 2014-12-12 |
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| catalystActivity | [CatalystActivity:9631979] D-glucose:sodium symporter activity of SLC5A1 mutants [plasma membrane] |
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| compartment | [Compartment:876] plasma membrane
[Compartment:984] extracellular region |
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| created | [InstanceEdit:5656371] Jassal, Bijay, 2014-12-12 |
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| disease | [Disease:5655824] glucose intolerance |
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| edited | [InstanceEdit:5656371] Jassal, Bijay, 2014-12-12 |
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| entityFunctionalStatus | [EntityFunctionalStatus:5656379] loss_of_function of SLC5A1 mutants [plasma membrane] |
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| input | [SimpleEntity:70115] Glc [extracellular region]
[SimpleEntity:74113] Na+ [extracellular region] |
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| isChimeric | FALSE |
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| literatureReference | [LiteratureReference:5656380] Structure of the human Na+/glucose cotransporter gene SGLT1
[LiteratureReference:5656382] Molecular basis for glucose-galactose malabsorption |
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| modified | [InstanceEdit:5663019] Jassal, Bijay, 2015-01-14
[InstanceEdit:6789777] Jassal, Bijay, 2015-08-04
[InstanceEdit:6789883] Jassal, Bijay, 2015-08-05
[InstanceEdit:6793492] Jassal, Bijay, 2015-09-01
[InstanceEdit:9628509] D'Eustachio, Peter, 2018-11-08
[InstanceEdit:9631717] Wu, G, 2018-12-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 |
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| name | Defective SLC5A1 does not cotransport Glc and Na+ |
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| normalReaction |
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| releaseDate | 2015-09-22 |
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| releaseStatus | NEW |
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| reviewed | [InstanceEdit:6789776] Broer, Stefan, 2015-08-04 |
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| reviewStatus | [ReviewStatus:9821382] five stars |
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| species | [Species:48887] Homo sapiens |
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| stableIdentifier | [StableIdentifier:6797169] R-HSA-5656356.4 |
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| summation | [Summation:5656358] Sodium/glucose cotransporter 1 (SLC5A1 aka SGLT1) actively a... |
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| (hasEvent) | [Pathway:5656364] Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) [Homo sapiens] |
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| (updatedInstance) | [_UpdateTracker:9778467] Update Tracker - [FailedReaction:5656356] Defective SLC5A1 does not cotransport Glc and Na+ - v68:[addCatalystActivity] |
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